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目的 :探讨高频率超声图像中乳腺恶性肿块的边界特征“恶性晕”形成的病理机制 ,为乳腺肿块的鉴别诊断提供依据。方法 :对 4 5例乳腺恶性肿块的高频超声声像图边界回声和病理切片中肿块的边界组织构成进行回顾性对比分析 ,按照肿瘤细胞对周围组织浸润的程度对病理边界组织构成进行分级。结果 :4 5例乳腺恶性肿块中有 31例在声像图中出现了边界特征性声像图“恶性晕”征 ,出现率为 6 8.89%,有“恶性晕”的肿块边缘组织病理分级明显高于无“恶性晕”的肿块 (P<0 .0 1 )。结论 :乳腺恶性肿块在声像图中出现“恶性晕”的病理机制是肿瘤细胞向周围组织的直接浸润 ,没有“恶性晕”的乳腺恶性肿块周边主要为纤维组织包绕及淋巴细胞浸润。“恶性晕”征可作为超声诊断乳腺癌的边界特征
OBJECTIVE: To investigate the pathological mechanism of the formation of the malignant borderline of malignant breast tumor in high-frequency ultrasound images and provide the basis for the differential diagnosis of breast tumor. Methods: Forty-five cases of malignant breast masses were retrospectively analyzed on the boundary echoes of the high-frequency ultrasonographic echocardiography and the pathological sections of tumor mass. The pathological boundary tissues were graded according to the degree of tumor cells infiltrating into the surrounding tissues. Results: Thirty-one of 41 breast malignancies showed “malignant halo” signs in the sonogram, with a rate of 6 8.89%. The pathological grading on the margins of malignant tumors Higher than those without “malignant halo” (P <0.01). Conclusion: The pathological mechanism of “malignant halo” in malignant breast tumor is the direct infiltration of tumor cells into the surrounding tissues. The surrounding malignant breast masses without malignant halo are mainly surrounded by fibrous tissue and infiltration of lymphocytes. “Malignant halo” sign can be used as a borderline diagnosis of breast cancer ultrasound features