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目的探讨衢州市婴幼儿病毒性腹泻的病原学特点,为病毒性腹泻的防控提供参考依据。方法采集2011年9月-2012年12月在衢州市人民医院、衢州市妇女儿童医院就诊的5岁以下腹泻儿童粪便标本,并进行病毒核酸检测分析。结果对于152份粪便标本实验室检测结果显示,肠道腹泻病毒检出率高达55.26%,其中轮状病毒的阳性检出率最高,为42.11%,其次为诺如病毒11.18%,肠道腺病毒(1.97%),检出率差异有统计学意义。在季节分布上轮状病毒检出率比较差异有统计学意义,且以冬秋季节最高,诺如病毒检出率差异无统计学意义。不同性别、生活环境、年龄的检出率比较差异均无统计学意义。结论 2011年-2012年衢州市病毒性腹泻呈高发状态,其中轮状病毒和诺如病毒是主要的病原之一,肠道腺病毒的检出率较低。应加强对病毒性腹泻,尤其是婴幼儿病毒性腹泻的监测。
Objective To explore the etiological characteristics of viral diarrhea in infants and young children in Quzhou and to provide reference for prevention and control of viral diarrhea. Methods Stool specimens from children under 5 years of age treated at Quzhou People’s Hospital and Quzhou Women and Children Hospital from September 2011 to December 2012 were collected and tested for viral nucleic acid. Results The results of laboratory tests on 152 stool specimens showed that the detection rate of intestinal diarrhea virus was as high as 55.26%, of which rotavirus positive rate was the highest (42.11%), followed by Norovirus (18.18%), intestinal adenovirus (1.97%), the detection rate difference was statistically significant. There was significant difference in the distribution of rotavirus between the seasons and the winter and autumn seasons. No significant difference was found in the detection rate of Norovirus. There was no significant difference in the detection rates of different gender, living environment and age. Conclusions From 2011 to 2012, the viral diarrhea in Quzhou showed a high incidence. Among them, rotavirus and Norovirus were the major pathogens, and the detection rate of enteric adenovirus was low. Viral diarrhea should be strengthened, especially in infants and young children with viral diarrhea monitoring.