目的探讨乳癌根治术后负压引流并皮瓣固定术的临床应用价值。方法术后在胸骨旁经肋下和腋中线置Ｙ型国产乳腺引流管进行持续负压吸引，距皮缘５～１０ｃｍ分别把皮肤与胸壁固定６针。结果１１２例手术切口均一期愈合，仅４例出现局部皮下少量积液。结论此方法可明显降低创口皮缘的坏死率，防止了皮下积液、积血的发生 Objective To investigate the clinical application value of negative pressure drainage and flap fixation after radical mastectomy. Methods Y-type internal mammary ductal drainage tube was placed in the substernal and subaxillary line for continuous suction under the sternal line. Five to 10 cm from the skin edge fixed 6 needles on the skin and chest wall, respectively. Results All the 112 surgical incisions healed at one time, and only 4 patients had local subcutaneous effusion. Conclusion This method can significantly reduce the necrosis rate of the wound margin and prevent the occurrence of subcutaneous effusion and hemorrhage.