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近年有关结核性腹膜炎诊断的主要进展是测定腹水腺苷脱氨酶(ADA)活性。抗原激发CD_4~+淋巴细胞分泌的γ干扰素是激活巨噬细胞的主要淋巴因子,后者可增强对结核杆菌的杀菌活力。有报道称结核性胸、腹膜炎的胸、腹水中有高浓度γ干扰素。作者前瞻性测定结核性腹膜炎腹水中γ干扰素浓度以确定其作为快速、非侵入性诊断结核性腹膜炎的价值。 病人及方法:92例相继有腹水的患者接受了腹腔镜检查。其中30例为结核性腹膜炎,21例为恶性肿瘤所致腹水,41例肝硬化腹水。取
A major advance in the diagnosis of tuberculous peritonitis in recent years has been the determination of ascitic adenosine deaminase (ADA) activity. Antigen-stimulated γ-interferon secreted by CD 4 + lymphocytes is a major lymphokine that activates macrophages, which enhances the bactericidal activity of Mycobacterium tuberculosis. There are reports that tuberculosis chest, peritonitis in the chest, ascites in high concentrations of interferon gamma. The authors prospectively determined the concentration of interferon-gamma in ascites of tuberculous peritonitis to determine its value as a rapid, noninvasive diagnosis of tuberculous peritonitis. Patients and Methods: A total of 92 patients with ascites received laparoscopy. Among them, 30 cases were tuberculous peritonitis, 21 cases were ascites caused by malignant tumors and 41 cases were ascites due to liver cirrhosis. take