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目的了解广州市2013-2015年登革热发病情况及健康人群抗体水平,为深入分析疫情来源及开展疫情预警预测提供参考。方法对中国疾病预防控制信息系统登革热疫情资料及健康人群血清登革热Ig G抗体检测结果进行描述性统计分析。结果 2013-2015年全市共报告登革热本地病例38 558例,发病率分别为9.71/10万、289.35/10万和0.52/10万,其中中心城区发病率高于周边城区(P<0.05);3年间健康人群抗体阳性率分别为为10.32%、10.02%、10.04%,中心城区抗体阳性率(12.31%)高于周边城区(6.71%),差异有统计学意义(P<0.05)。少儿组抗体阳性率最低,同一年不同年龄组之间抗体阳性率比较差异有统计学意义(P<0.05)。结论广州市健康人群登革热抗体阳性率保持在较高水平,并有随年龄增大而逐步升高的趋势,存在隐性感染引发本地暴发疫情的风险。
Objective To understand the incidence of Dengue Fever and antibody levels in healthy population from 2013 to 2015 in Guangzhou City and provide reference for further analysis of the origin of the epidemic and the prediction of the epidemic situation. Methods Descriptive statistical analysis was conducted on the data of dengue fever in China’s disease prevention and control information system and the Ig G antibody test results of serum dengue in healthy population. Results A total of 38 558 local cases of dengue were reported in the city from 2013 to 2015, with a prevalence of 9.71 / 100000, 289.35 / 100000 and 0.52 / 100000, respectively. The incidence rate of central urban area was higher than that of the surrounding urban areas (P <0.05); 3 The positive rates of antibody in healthy population were 10.32%, 10.02% and 10.04%, respectively. The positive rate of antibody in central area (12.31%) was higher than that in surrounding area (6.71%), the difference was statistically significant (P <0.05). The positive rate of antibody in children group was the lowest, the positive rate of antibody in different age groups in the same year was significantly different (P <0.05). Conclusions The positive rate of Dengue antibody in healthy population in Guangzhou maintains a high level, and gradually increases with age. There is a risk of latent infection causing local outbreak.