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目的:比较利巴韦林注射液与热毒宁注射液分别用于治疗小儿急性上呼吸道感染患者的临床疗效。方法:选取儿科2014年3月—2015年3月间收治的急性上呼吸道感染患儿122例,将其随机分为观察组与对照组每组,各61例;观察组患者给予热毒宁注射液治疗,对照组患者给予利巴韦林注射液治疗,比较两组患者临床症状、体征缓解及消退时间以及两组患者治疗后总有效率及药物不良反应的发生率。结果:治疗后,观察组患者退热、止咳、咽痛消失、鼻塞流涕症状消失时间明显短于对照组(P<0.05);观察组患者的总有效率为95.08%显著高于对照组为80.33%(P<0.05);两组患儿用药后均无严重不良反应发生。结论:热毒宁注射液用于治疗小儿急性上呼吸道感染患者临床疗效优于利巴韦林注射液。
OBJECTIVE: To compare the clinical efficacy of ribavirin injection and reverinax injection for the treatment of children with acute upper respiratory tract infection. Methods: A total of 122 children with acute upper respiratory tract infection who were admitted to our hospital from March 2014 to March 2015 were randomly divided into observation group (61 cases) and control group (61 cases). Patients in observation group The patients in the control group were treated with ribavirin injection. The clinical symptoms, symptom relief and extinction time were compared between the two groups. The total effective rate and the incidence of adverse drug reactions were compared between the two groups after treatment. Results: After treatment, the patients in the observation group had fever, cough and sore throat disappeared, the disappearance time of nasal obstruction and runny nose was significantly shorter than that of the control group (P <0.05); the total effective rate in the observation group was 95.08% 80.33% (P <0.05). There was no serious adverse reactions in both groups after treatment. Conclusion: The clinical effect of Revedunin injection for the treatment of children with acute upper respiratory tract infection is superior to ribavirin injection.