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用ELISA方法检测了29名慢性迁延性肝炎患者和18名健康献血员血清可溶性白细胞介素2受体(sIL-2R)水平,同时进行了血清IL-2与sIL-2R的相关分析。结果发现,正常人sIL-R为147±72.1u/ml,而慢性迁延性肝炎病人sIL-2R显著升高(210.5±84).GWe治疗3个月后sIL-2水平显著下降(185.8±79);同时发现IL-2水平与sIL-2R 有一定相关性。上述结果提示GWe具有调节机体IL-2功能的独特作用。
Serum soluble interleukin 2 receptor (sIL-2R) levels were measured in 29 patients with chronic persistent hepatitis and 18 healthy blood donors by ELISA. Serum IL-2 and sIL-2R levels were also analyzed. The results showed that sIL-R was 147 ± 72.1u / ml in normal controls and sIL-2R was significantly increased in patients with chronic persistent hepatitis (210.5 ± 84), sIL-2 was significantly decreased after 3 months of treatment (185.8 ± 79 ). At the same time, IL-2 level was found to be correlated with sIL-2R. These results suggest that GWe has a unique role in regulating the function of IL-2 in the body.