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作者对20例慢性乙肝患者进行肝穿活检,并对肝细胞内乙肝病毒抗原含量分组进行定量测定。1组(慢性活动型,HBsAg在肝细胞胞膜上表达为粗颗粒膜型,HBcAg为胞膜型)其病毒抗原含量明显高于2组(小叶型肝炎,HBsAg为细颗粒膜型,HBcAg为胞膜型).1组与3组(HBsAg为胞浆型,HBcAg为胞核型)抗原含量无差异。提示肝损程度与肝细胞膜上表达的HBcAg含量多少有关。
The author of 20 cases of chronic hepatitis B patients with liver biopsy, and liver cells in hepatitis B virus antigen content group quantitative determination. 1 group (chronic active type, HBsAg is expressed on the membrane of hepatocyte as coarse granular membrane type and HBcAg is membrane type), the virus antigen content was significantly higher than that of the two groups (small leaf type hepatitis, HBsAg was fine granular type, HBcAg was Membrane type). There was no difference in antigen content between groups 1 and 3 (cytoplasmic HBsAg and cytoplasmic HBcAg). Tip liver damage and liver cell membrane expression of HBcAg content of how much.