细胞凋亡是新近提出的有关细胞死亡的一种模式，其形态学和生化改变均明显不同于病理性坏死。细胞凋亡的甄别是有关研究中遇到的主要问题之一。目前有关细胞凋亡的判别方法和标准很多，但均有各自的局限性。本文综述了细胞凋亡的形态学和生化特征，以及当前用于甄别细胞凋亡的研究方法，并分析了各种方法的原理及优缺点 Apoptosis is a recently proposed model of cell death that differs markedly from morphological and biochemical changes in pathological necrosis. Screening for apoptosis is one of the major problems encountered in the study. At present there are many methods and standards for judging apoptosis, but all have their own limitations. This review summarizes the morphological and biochemical features of apoptosis, as well as the current research methods used to screen for apoptosis, and analyzes the principles, advantages and disadvantages of various methods