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目的:探讨夫西地酸乳膏治疗女童细菌性外阴阴道炎的疗效和安全性。方法:女童细菌性外阴阴道炎患者178例,随机分为夫西地酸组92例,莫匹罗星组86例,两组均每天2次外阴用药,连续7天,停药3～7天后复诊评估疗效和不良反应。结果:两种药物治疗女童细菌性生殖器官炎症有效率分别为:夫西地酸组90.22%、莫匹罗星组89.54%,两组有效率比较无统计学差异(P>0.05)。两组均未发现严重不良反应。结论:夫西地酸乳膏治疗女童细菌性生殖器官炎症疗效确定,比莫匹罗星软膏的外阴刺激性小,更容易被女童接受。
Objective: To investigate the efficacy and safety of fusidic acid cream in the treatment of bacterial vulvovaginitis in girls. Methods: A total of 178 girls with bacterial vulvovaginitis were divided into two groups: 92 cases of fusidic acid group and 86 cases of mupirocin group. The two groups were treated with genital 2 times daily for 7 days and stopped for 3 to 7 days Visit to assess efficacy and adverse reactions. Results: The rates of bacterial genital inflammation in the two kinds of drugs were 90.22% for foxydine and 89.54% for mupirocin, respectively. There was no significant difference between the two groups (P> 0.05). No serious adverse reactions were found in either group. Conclusion: Fusidic acid cream treatment of bacterial inflammation of the girl reproductive organs to determine the efficacy of Mupirocin ointment than the vulva irritation of small, more easily accepted by girls.