由于超声诊断技术的进步,经母体腹壁进行脐带穿刺采血(PUBS)法已广泛应用于临床。与传统的非损伤性检查法相比,虽然有可能引起胎儿的心动过缓、出血等合并症,但通过PUBS进行的血分析等仍是评价胎儿状况的重要指标。 一、适应症 随时代和医学背景不断发展和变迁,最初多用于胎儿畸形行染色体检查,IUGR、胎儿水肿、Rh血型不合者次之。近年,IUGR、胎儿宫内感染、先天性代谢异常、羊水量异常等适应症逐渐增多,特别是重 Due to advances in ultrasonic diagnostic techniques, umbilical cord blood collection (PUBS) via the abdominal wall of the mother has been widely used clinically. Compared with the traditional non-invasive test, although it may cause fetal bradycardia, bleeding and other complications, but by PUBS blood analysis is still an important indicator to assess the status of the fetus. First, the indications With the times and the continuous development of medical background and changes, initially more used for fetal malformations chromosome examination, IUGR, fetal edema, Rh blood group followed by non-compliance. In recent years, IUGR, fetal intrauterine infection, congenital metabolic abnormalities, amniotic fluid abnormalities and other indications gradually increased, especially heavy