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目的观察输血前不规则抗体检查的应用价值及临床意义。方法取2015年1月~2016年1月医院择期手术需要输血治疗患者13146例,设为观察组,患者输血前进行不规则抗体检查。取2014年1月~2015年1月医院择期手术需要输血患者12208例,设为对照组,患者输血前不进行规则抗体检查,分析不规则抗体检查价值及两组输血反应发生率情况。结果观察组13146例患者中,检测出116例不规则抗体,检出率为0.865%。其中,101例为特异性不规则抗体,占0.753%,15例为非特异性不规则抗体,检出率为0.112%;观察组患者中不规则抗体检出率与性别、输血次数及是否有妊娠史有关,且女性检出率高于男性(P<0.05),患者输血次数越多并且伴有妊娠史者检出率较高;观察组输血后不良反应发生率,低于对照组(P<0.05)。结论择期手术患者输血前加强不规则抗体检查效果理想,能降低输血发生率,提高输血安全,值得推广应用。
Objective To observe the value and clinical significance of irregular antibody test before transfusion. Methods From January 2015 to January 2016, 13,146 patients undergoing elective transsexual surgery were enrolled in this study. Patients were randomly divided into observation group and irregular antibody test before transfusion. From January 2014 to January 2015, 12,208 transfusions were performed in patients undergoing elective surgery in our hospital. The patients were divided into control group. Regular antibody test was not performed before transfusion, and the value of irregular antibody test and the incidence of transfusion reactions were analyzed. Results Of the 13,146 patients in the observation group, 116 irregular antibodies were detected, with a detection rate of 0.865%. Among them, 101 cases of specific irregular antibodies, accounting for 0.753%, 15 cases of nonspecific irregular antibodies, the detection rate was 0.112%; the observation group of patients with irregular antibody detection rate and gender, the number of transfusions and the presence or absence of pregnancy (P <0.05). The higher the number of blood transfusions and the higher the detection rate of patients with pregnancy were, the incidence of adverse reactions in the observation group was lower than that of the control group (P < 0.05). Conclusions Elective antihypertensive drugs before blood transfusion in patients undergoing elective surgery are effective and can reduce the incidence of transfusion and improve the safety of blood transfusion, which is worthy of popularization and application.