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目的探讨精子密度、存活率、活动力(a+b),形态与宫腔内人工授精妊娠结局的相关性。方法选自以男性不育为因素289对夫妇进行IUI周期治疗:在授精日,取男方精液进行计算机综合分析,常规方法授精后,将其精液检测结果与妊娠结局相比较。结果精子密度、存活率、活力(a+b)%、形态与IUI妊娠结局概率分别是:15.2%,16.3%,16.9%,18.7%;精子密度组:(30~60)×106/ml与(60~90)×106/ml、≥100×106/ml、≤20×106/ml比较有差异性P<0.01;存活率组:30%~60%与60%~80%、≥80%比较有差异性P<0.01;活力组:30%~45%与10%~20%、20%~30%、>50%组间比较有差异性P<0.01;形态组:<15%组与a>30%与30%≥A≥15%比较有差异性P<0.01。结论精子密度、存活率、活力(a+b)%、形态与IUI妊娠结局密切相关,可以作为评价宫腔内人工授精的一项实验室指标;精子形态与IUI妊娠结局呈正相关;精子较低{密度、活率、活力(a+b)%}与IUI妊娠结局呈正相关;单纯性男性少、弱精子症在IUI周期中能获得较高的妊娠率。
Objective To investigate the correlation between sperm density, survival rate, motility (a + b), morphology and intrauterine pregnancy outcome of artificial insemination. Methods: Male infertility as a factor 289 couples IUI cycle treatment: on the day of fertilization, male semen was taken for comprehensive computer analysis, routine methods of insemination, the semen test results compared with pregnancy outcomes. Results Sperm density, survival rate, viability (a + b)%, morphology and IUI pregnancy outcomes were 15.2%, 16.3%, 16.9% and 18.7% respectively; sperm density group (30-60) (60 ~ 90) × 106 / ml, ≥100 × 106 / ml, ≤20 × 106 / ml, the difference P <0.01; survival rate group: 30% ~ 60% and 60% ~ 80%, ≥80% The difference was significant (P <0.01). In the vitality group, the difference was significant between 30% -45% and 10% -20%, 20% -30%, and> 50% a> 30% and 30%> A> 15%, there is a difference P <0.01. Conclusions Sperm density, survival rate, vitality (a + b)%, morphology are closely related to pregnancy outcome of IUI, which can be used as a laboratory index to evaluate intrauterine insemination. Sperm morphology is positively correlated with IUI pregnancy outcome. {Density, viability, vitality (a + b)%} and IUI pregnancy outcome was positively correlated; simple men, weak sperm disease in the IUI cycle can get a higher pregnancy rate.