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目的观察银杏达莫联合腺苷钴胺治疗糖尿病周围神经病变的临床疗效。方法将62例糖尿病周围神经病变患者随机分为治疗组、对照组,各31例;治疗组给予银杏达莫联合腺苷钴胺治疗,对照组单用腺苷钴胺治疗。两组疗程均为20天,观察周围神经传导速度变化情况,并评价临床疗效。结果治疗组、对照组总有效率分别为87.1%、58.1%;组间临床疗效比较,差异有统计学意义(P<0.05)。治疗前后组内比较,两组正中神经、尺神经、腓总神经的运动神经及正中神经、尺神经、腓浅神经的感觉神经传导速度差异均有统计学意义(P<0.05,P<0.01);组间治疗后比较,各指标差异均有统计学意义(P<0.05)。结论银杏达莫联合腺苷钴胺治疗糖尿病周围神经病变疗效良好。
Objective To observe the clinical efficacy of gingko dipyridamole and adenosylcobalamin in the treatment of diabetic peripheral neuropathy. Methods Sixty-two patients with diabetic peripheral neuropathy were randomly divided into treatment group and control group, with 31 cases in each group. The treatment group was treated with gingko-damo combined with adenosylcobalamin and the control group with adenosine alone. The two groups were treated for 20 days, observed peripheral nerve conduction velocity changes, and evaluate the clinical efficacy. Results The total effective rates of the treatment group and the control group were 87.1% and 58.1% respectively. There was significant difference between the two groups in clinical efficacy (P <0.05). After treatment, the sensory nerve conduction velocity of the median nerve, ulnar nerve and common peroneal nerve between the two groups were significantly different (P <0.05, P <0.01) After treatment, the differences of each index were statistically significant (P <0.05). Conclusion Ginkgo biloba combined with adenosylcobalamin in the treatment of diabetic peripheral neuropathy has a good effect.