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目的 :探讨联合使用阿托伐他汀与阿司匹林预防脑梗死复发的临床效果。方法 :对2013年1月~2015年5月期间我院收治的194例脑梗死患者的临床资料进行回顾性分析。我院按照随机数表法将这194例患者分为对照组和观察组,每组各有97例患者。我院对对照组患者使用阿司匹林进行治疗,对观察组患者联合使用阿托伐他汀与阿司匹林进行治疗,然后比较两组患者的治疗效果。结果 :观察组患者TC、TG与LDL-C的水平明显低于对照组患者,观察组患者HDL-C的水平明显高于对照组患者,二者之间差异显著(P<0.05),具有统计学意义。观察组患者在治疗期间脑梗死的复发率为5.2%,对照组患者在治疗期间脑梗死的复发率为16.5%。观察组患者在治疗期间脑梗死的复发率明显低于对照组患者,差异显著(P<0.05),具有统计学意义。结论 :联合使用阿托伐他汀与阿司匹林预防脑梗死复发的临床效果显著,可有效地改善脑梗死患者的血脂水平,并遏制其血栓的形成。此法值得在临床上推广应用。
Objective: To investigate the clinical efficacy of combination of atorvastatin and aspirin in preventing recurrent cerebral infarction. Methods: The clinical data of 194 patients with cerebral infarction admitted to our hospital from January 2013 to May 2015 were retrospectively analyzed. Our hospital in accordance with the random number table method of these 194 patients were divided into control group and observation group, each with 97 patients. In our hospital, patients in the control group were treated with aspirin, atorvastatin and aspirin in the observation group were treated, and then the treatment effect was compared between the two groups. Results: The levels of TC, TG and LDL-C in the observation group were significantly lower than those in the control group. The HDL-C level in the observation group was significantly higher than that in the control group (P <0.05) Significance of learning. In the observation group, the recurrence rate of cerebral infarction was 5.2% in the treatment group, and the recurrence rate of the cerebral infarction in the control group was 16.5% during the treatment period. The recurrence rate of cerebral infarction in the observation group was significantly lower than that in the control group during treatment, the difference was significant (P <0.05), with statistical significance. Conclusion: The combination of atorvastatin and aspirin in the prevention of recurrent cerebral infarction has a significant clinical effect, which can effectively improve the level of blood lipids in patients with cerebral infarction and prevent the formation of thrombus. This method is worth promoting in clinical application.