In order to better understand the development level of eco-efficiency in Southeast Guizhou’s experimental area of eco-civilization construction,we conduct dynamic comparison research of its eco-efficiency and the national eco-efficiency,using single ratio method based on the ecological footprint model,to grasp the gap between its eco-efficiency and the national eco-efficiency,so that we can take appropriate countermeasures to improve eco-efficiency. The results show that in the period 1978-2010,the eco-efficiency in Southeast Guizhou’s experimental area of eco-civilization construction was always lower than the national eco-efficiency; the long-time average annual value of its eco-efficiency was less than one half of that of the national eco-efficiency,with the absolute gap of 1 630. 095 yuan /hm 2 ,and the gap tended to widen year by year in the period 1978-2002 ( the gap increased from 276. 551 yuan /hm 2 in 1978 to peak of 3 227. 713 yuan /hm 2 in 2002,with an average annual increase of 118. 047 yuan /hm 2 ,and especially after 1992,the gap was particularly evident,with an average annual increase of 194.771 yuan/hm 2 ) ,but from 2003,the gap between the two tended to decrease. Based on the prediction results of grey system,in the period 2011-2025,the gap between the eco-efficiency in Southeast Guizhou’s experimental area of eco-civilization construction and the national eco-efficiency will gradually narrow,and from 2019, the eco-efficiency in Southeast Guizhou’s experimental area of eco-civilization construction will be higher than the national eco-efficiency. In order to better understand the development level of eco-efficiency in Southeast Guizhou’s experimental area of ​​eco-civilization construction, we conduct dynamic comparison research of its eco-efficiency and the national eco-efficiency, using single ratio method based on the ecological footprint model , to grasp the gap between its eco-efficiency and the national eco-efficiency, so that we can take appropriate countermeasures to improve eco-efficiency. The results show that in the period 1978-2010, the eco-efficiency in Southeast Guizhou’s experimental area of-eco-civilization construction was always lower than the national eco-efficiency; the long-time average annual value of its eco-efficiency was less than one half of that of the national eco-efficiency, with the absolute gap of 1 630. 095 yuan / hm 2, and the gap tended to widen year by year in the period 1978-2002 (the gap increased from 276. 551 yuan / hm 2 in 1978 to peak of 3 227. 713 yuan / hm 2 in 2002, with an average annual increas e of 118. 047 yuan / hm 2, and especially after 1992, the gap was particularly evident, with an average annual increase of 194.771 yuan / hm 2), but from 2003, the gap between the two tended to decrease. Based on the prediction results of gray system, in the period 2011-2025, the gap between the eco-efficiency in Southeast Guizhou’s experimental area of ​​eco-civilization construction and the national eco-efficiency will gradually narrow, and from 2019, the eco-efficiency in Southeast Guizhou’s experimental area of ​​eco-civilization construction will be higher than the national eco-efficiency.