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[期刊论文] 作者：Jinyuan Zhao,Zhigang Hu,Bing Xiong,Keqin Li,
来源：中国通信（英文版） 年份：2018
The growing trend of network vir-tualization results in a widespread adoption of virtual switches in virtualized environments. However, virtual switching is con...
[会议论文] 作者：Mengzhu Xue,Bing Xiong,Xin Xie,Hualiang Jiang,Jingkang Shen,
来源：2009长三角药物化学研讨会 年份：2009
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[期刊论文] 作者：Bibo YAN,Mengzhu XUE,Bing XIONG,Ke LIU,Dingyu HU,Jingkang SHEN,
来源：中国药理学报(英文版) 年份：2009
Aim:The search for molecules whose bioactivities are similar to those of given compounds or to optimize the initial lead compounds from high throughput screenin...
Identification and Optimization of 2-thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromod
[会议论文] 作者：Lele Zhao,Danyan Cao,Jianhua He,Bing Xiong,Zehong Miao,Jingkang Shen,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Epigenetic pathways can modulate gene expression by controlling and interpreting chromatin modifications....
[期刊论文] 作者：Yanxiong E,Zhibiao Hao,Jiadong Yu,Chao Wu,Lai Wang,Bing Xiong,Jian Wang,
来源：中国物理B（英文版） 年份：2017
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[期刊论文] 作者：Danqi Chen,Aijun Shen,Guanghua Fang,Hongchun Liu,Minmin Zhang,Shuai Tang,Bing Xiong,
来源：药学学报（英文版） 年份：2016
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[期刊论文] 作者：LI Qian,YANG Zhi-hui,CHAI Li-yuan,WANG Bing,XIONG Shan,LIAO Ying-ping,ZHANG Shu-juan,
来源：中南大学学报（英文版） 年份：2013
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[会议论文] 作者：Jing Ren,Jian Li,Tong Chen,Yechun Xu,Bing Xiong,Jianhua He,Jingkang Shen,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
HSP90(heat shock protein 90) is a molecular chaperone to assist other proteins folding properly in response to cell stress,and is one of the most abundant proteins expressed in cells.Recent studies we...
Sulfated polymannuroguluronate inhibits Tat-induced SLK cell adhesion via a novel binding site, a KK
[期刊论文] 作者：Yan-lin WU,Jing AI,Jing-ming ZHAO,Bing XIONG,Xiao-jie XIN,Mei-yu GENG,Xian-liang XIN,Han-dong JIANG,
来源：中国药理学报（英文版） 年份：2011
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,Conformational flexibility of β-secretase: molecular dynamics simulation and essential dynamics ana
[期刊论文] 作者：Bing XIONG,Xiao-qin HUANG,Ling-ling SHEN,Jian-hua SHEN,Xiao-min LUO,Xu SHEN,Hua-liang JIANG,Kai-xian,
来源：中国药理学报（英文版） 年份：2004
AIM: Based on the structural analysis to reveal the mechanism of ligand binding to β-secretase and the specificity of each binding sub-site. METHODS: Molecular...
[会议论文] 作者：Bing Xiong,Feng Shi,Jing Ren,Danqi Chen,Yechun Xu,Naixia Zhang,Jianhua He,Jingkang Shen,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
HSP90(heat shock protein 90)is a molecular chaperone to assist other proteins folding properly in response to cell stress,and is one of the most abundant pr...
[期刊论文] 作者：Yue-hong Chen,Hao Lv,Ning Shen,Xiao-min Wang,Shuai Tang,Bing Xiong,Jian Ding,Mei-yu Geng,Min Huang,
来源：中国药理学报（英文版） 年份：2020
KRAS is one of the most important proto-oncogenes.Its mutations occur in almost all tumor types,and KRAS mutant cancer is still lack of effective therapy.Prenyl...
Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relat
[期刊论文] 作者：Bin HU,Bing XIONG,Bei-ying QIU,Xin LI,Hai-ping YU,Kun XIAO,Xin WANG,Jia LI,Jing-kang SHEN,
来源：中国药理学报（英文版） 年份：2006
Aim: To develop probes for detecting the binding specificity between β-secretase and substrate, and provide reliable biological activity data for further resea...
Design, Synthesis and Biological Evaluation of 6-(2,6-dichloro-3,5-dimethoxyphenyl)-4-Substituted-1H
[会议论文] 作者：Zhen Zhang,Dongmei Zhao,Yang Dai,Maosheng Cheng,Meiyu Geng,Yuchi Ma,Jing Ai,Bing Xiong,Jingkang Shen,
来源：2016年长三角药物化学研讨会 年份：2016
Tyrosine kinase fibroblast growth factor receptor (FGFR),which is aberrant in various cancer types,is a promising target for cancer therapy[1-4].Thus,discovery of potent and selective FGFR inhibitors...
,Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing h
[期刊论文] 作者：Yiping ZHU,Kun XIAO,Haiping YU,Lanping MA,Bing XIONG,Haiyan ZHANG,Xin WANG,Jingya LI,Jia LI,Jingkang,
来源：中国药理学报(英文版) 年份：2009
Aim:The aim of this study was to design and synthesize a series of high activity compounds against aspartyl protease β-secretase (BACE-1) bearing hydroxyethyle...
[期刊论文] 作者：Zi-Wei Zhu,Ji-Yuan Zheng,Lai Wang,Bing Xiong,Chang-Zheng Sun,Zhi-Biao Hao,Yi Luo,Yan-Jun Han,Jian Wang,
来源：中国物理快报（英文版） 年份：2017
The wavelength-dependent and frequency-dependent dielectric function of wurtzite-GaN is calculated totally from fundamental parameters such as the lattice const...
[期刊论文] 作者：Danqi Chen,Aijun Shen,Guanghua Fang,Hongchun Liu,Minmin Zhang,Shuai Tang,Bing Xiong,Lanping Ma,Meiyu,
来源：Acta Pharmaceutica Sinica B 年份：2016
Histone acetylation is a critical process in the regulation of chromatin structure and gene expression.Histone deacetylases(HDACs)remove the acetyl group,leadin...
[期刊论文] 作者：Xuecheng Liu,Bing Xiong,Changzheng Sun,Jian Wang,Zhibiao Hao,Lai Wang,Yanjun Han,Hongtao Li,Jiadong Yu,
来源：中国光学快报（英文版） 年份：2021
A novel thin-film lithium niobate[TFLN]electro-optic modulator is proposed and demonstrated.LiNb03-silica hybrid wave-guide is adopted to maintain low optical loss for an electrode spacing as narrow as 3 pm,resulting in a low half-wave-volt......
[会议论文] 作者：Wuchen Xie,Tongchao Liu,Jianpeng Liang,Qiang Yin,Bing Xiong,Dongmei Zhao,Qidong You,Guohua Chen,Yue-Lei,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Introducing new methods for mild and stereoselective glycosylation(Scheme 1): For O-glycosides,1)Using beta-pinene as acid scavenger,direct glycosylation of taxanes was rendered possible for the first...
[会议论文] 作者：Qiancheng Shen,Mingyue Zheng,Xiaomin Luo,Cheng Luo,Xian Liu,Yun Du,Jing Li,Weiliang Zhu,Jingkang Shen,Bing Xiong,
来源：第十一届全国计算(机)化学学术会议 年份：2011
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