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[期刊论文] 作者：Xu Guan-Lei,Wang Xiao-Tong,Xu Xiao-Gang,
来源：中国物理B（英文版） 年份：2010
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Xyloketal B reduces cerebral infarction and neurologic deficits in a mouse transient middle cerebral
[会议论文] 作者：Ni PAN,Liu-yi LU,Jie LIU,Yong-yuan GUAN,Guan-lei WANG,
来源：中国药理学会北美分会药理学学术大会 年份：2017
The present study aimed to observe the effect of xyloketal B [Xyl-B,novel marine compound isolated from mangrove fungus Xylaria sp.(no.2508)] in a mouse mod...
,Interaction between Cl- channels and CRAC-related Ca2+ signaling during T lymphocyte activation and
[期刊论文] 作者：Guan-lei WANG,Yan QIAN,Qin-ying QIU,Xiu-jian LAN,Hua HE,Yong-yuan GUAN,
来源：中国药理学报（英文版） 年份：
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,Cellular mechanisms of reduced sarcoplasmic reticulum Ca2+ content in L-thyroxin-induced rat ventri
[期刊论文] 作者：Lai-jing SONG,Guan-lei WANG,Jie LIU,Qin-ying QIU,Jing-hua OU,Yong-yuan GUAN,
来源：中国药理学报（英文版） 年份：2008
Aim:To examine how the sarcoplasmic reticulum (SR) Ca2+ content changes and the underlying mechanism in L-thyroxin-induced cardiac hypertrophy. Methods:Echocard...
[期刊论文] 作者：Sammen Huang,Wenliang Chen,Jiyan Pang,Zhong Pei,Guan-Lei Wang,Hong-Shuo Sun,
来源：黑龙江科技信息 年份：2015
本文通过对荣华二采区10...
,WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cel
[期刊论文] 作者：Ya-juan ZHANG,Hua-qing ZHENG,Bao-yi CHEN,Lu SUN,Ming-ming MA,Guan-lei WANG,Yong-yuan GUAN,
来源：中国药理学报（英文版） 年份：2018
Hypotonic challenge evoked vascular cell proliferation through activation of volume-regulated Cl-channel (VRCC),leading to a decrease in the intracellular Cl-co...
,Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediate
[期刊论文] 作者：Can-zhao Liu,Fei-ya Li,Xiao-fei Lv,Ming-ming Ma,Xiang-yu Li,Cai-xia Lin,Guan-lei Wang,Yong-yuan Guan,
来源：中国药理学报（英文版） 年份：2020
TMEM16A Ca2+-activated chloride channel (CaCC) plays an essential role in vascular homeostasis.In this study we investigated the molecular mechanisms underlying...
,Neuroprotective effects of volume-regulated anion channel blocker DCPIB on neonatal hypoxic-ischemi
[期刊论文] 作者：Ammar ALIBRAHIM,Li-yan ZHAO,Christine You-jin BAE,Andrew BARSZCZYK,Christopher LF SUN,Guan-lei WANG,Hong-shuo,
来源：中国药理学报（英文版） 年份：2013
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[期刊论文] 作者：Bao-yi Chen,Cheng-cui Huang,Xiao-fei Lv,Hua-qing Zheng,Ya-juan Zhang,Lu Sun,Guan-lei Wang,Ming-ming Ma,
来源：中国药理学报（英文版） 年份：2020
Serum-and glucocorticoid-inducible kinease-1 (SGK1) is a serine/threonine kinase regulated by hypotonic stimuli,which is involved in regulation of cell cycle an...
Cystic Fibrosis Transmembrane Conductance Regulator(CFTR)prevents apoptosis induced by hydrogen pero
[会议论文] 作者：Jia-Wei Zeng,Xue-Lin Zeng,Ming-Ming Ma,Feng Yuan,Jie Liu,Xiao-Fei Lv,Guan-Lei Wang,Yong-Yuan Guam,Fei-Ya,
来源：2015广东省药师周大会 年份：2014
Cystic fibrosis transmembrane conductance regulator (CFTR) acts as a cAMP-dependent chloride channel,has been studied in various types of cells.CFTR is abun...
Cystic Fibrosis Transmembrane Conductance Regulator(CFTR)prevents apoptosis induced by hydrogen pero
[会议论文] 作者：Jia-Wei Zeng,Xue-Lin Zeng,Fei-Ya Li,Ming-Ming Ma,Feng Yuan,Jie Liu,Xiao-Fei Lv,Guan-Lei Wang,Yong-Yuan,
来源：2015广东省药师周大会 年份：2014
Cystic fibrosis transmembrane conductance regulator (CFTR) acts as a cAMP-dependent chloride channel,has been studied in various types of cells.CFTR is abundantly expressed in vascular smooth muscle c...
[期刊论文] 作者：Da-yue DUAN,Luis LH LIU,Nathan BOZEAT,Z Maggie HUANG,Sunny Y XIANG,Guan-lei WANG,Linda YE,Joseph R HUME,
来源：中国药理学报（英文版） 年份：2005
In comparison to cation (K+, Na+, and Ca2+) channels, much less is currently known about the functional role of anion (Cl-) channels in cardiovascular physiolog...
,Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic br
[期刊论文] 作者：Raymond WONG,Ahmed ABUSSAUD,Joseph WH LEUNG,Bao-feng XU,Fei-ya LI,Sammen HUANG,Nai-hong CHEN,Guan-lei WANG,
来源：中国药理学报（英文版） 年份：2018
Activation of swelling-induced CI current (IC1,swell) during neonatal hypoxia-ischemia (HI) may induce brain damage. Hypoxic-ischemic brain injury causes chroni...
,Effects of SLCO1B1 and GATM gene variants on rosuvastatin-induced myopathy are unrelated to high pl
[期刊论文] 作者：Xue Bai,Bin Zhang,Ping Wang,Guan-lei Wang,Jia-li Li,Ding-sheng Wen,Xing-zhen Long,Hong-shuo Sun,Yi-bin,
来源：中国药理学报（英文版） 年份：2019
Myotoxicity is a significant factor contributing to the poor adherence and reduced effectiveness in the treatment of statins.Genetic variations and high drug pl...
[会议论文] 作者：Jing TAO,Can-zhao LIU,Jing YANG,Zhi-zhong XIE,Ming-ming MA,Xiang-yu LI,Fei-ya LI,Guan-lei WANG,Jia-guo,
来源：中国药理学会北美分会药理学学术大会 年份：2017
Recent evidence suggested that ClC-3,encoding Cl-channel or Cl-/H+antiporter,plays a critical role in regulation of a variety of physiological functions....
,Xyloketal B exerts antihypertensive effect in renovascular hypertensive rats via the NO-sGC-cGMP pa
[期刊论文] 作者：Guo-hao WANG,Xiao-fei LV,Wei-feng MENG,Wen-liang CHEN,Ji-yan PANG,Yong-cheng LIN,Hong-shuo SUN,Guan-lei WANG,
来源：中国药理学报（英文版） 年份：2018
Xyloketal B (Xyl-B) is a novel marine compound isolated from mangrove fungus Xylaria sp. (No 2508). We previously showed that Xyl-B promoted endothelial NO rele...
TMEM16A contributes to endothelial dysfunction by facilitating Nox2 NADPH oxidase-derived reactive o
[会议论文] 作者：Ming-ming MA,Yan-hua DU,Xue-lin ZENG,Jia-guo ZHOU,Xiang-yu LI,Xiao-fei LV,Guan-lei WANG,Lu SUN,Yong-yuan,
来源：中国药理学会北美分会药理学学术大会 年份：2017
Ca2+-activated Cl- channels play a crucial role in various physiological processes.However,the role of TMEM16A in vascular endothelial dysfunction during hy...
TMEM16A contributes to endothelial dysfunction by facilitating Nox2 NADPH oxidase-derived reactive o
[会议论文] 作者：Ming-ming MA,Min GAO,Kai-min GUO,Mi WANG,Xiang-yu LI,Xue-lin ZENG,Lu SUN,Xiao-fei LV,Yan-hua DU,Guan-lei WANG,
来源：中国药理学会北美分会药理学学术大会 年份：2017
Ca2+-activated Cl- channels play a crucial role in various physiological processes.However,the role of TMEM16A in vascular endothelial dysfunction during hypertension is unclear....
,Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammati
[期刊论文] 作者：Wen,Xiong-qing Huang,Jie-yi Du,Hong-shuo Sun,Zhu-xiao Ren,Jie Liu,Yong-yuan Guan,Xiao-miao Zhao,Guan-lei Wang,
来源：中国药理学报（英文版） 年份：2019
Obesity induces accumulation of adipose tissue macrophages (ATMs) and ATM-driven inflammatory responses that promote the development of glucose and lipid metabo...
,Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppr
[期刊论文] 作者：WEN,Jian-ding CHENG,Jian-wen CHEN,Ji-yan PANG,Jie LIU,Yong-yuan GUAN,Li-yan ZHAO,Wen-liang CHEN,Guan-lei WANG,
来源：中国药理学报（英文版） 年份：2017
Xyloketal B (Xyl-B) is a novel marine compound isolated from mangrove fungus Xylaria sp.We previously demonstrated that pretreatment with Xyl-B exerted neuropro...
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