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Phytochemical Guttiferone K Triggers Apoptosis Through Inducing Endoplasmic Reticulum Stress Aggrava
[会议论文] 作者：Kai-Kei Miu,Ge Lin,Kenneth Kin-Wah To,Hong-Xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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Endoplasmic reticulum stress aggravation as the mechanism underlying Guttiferone K-induced apoptosis
[会议论文] 作者：Kai-kei MIU,Ge LIN,Kenneth Kin-wah TO,Hong-xi XU,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
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Phytochemical Guttiferone K Triggers Apoptosis Through Inducing Endoplasmic Reticulum Stress Aggrava
[会议论文] 作者：Kai-Kei Miu,Kenneth Kin-Wah To,Hong-Xi Xu,Ge Lin,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Guttiferone K (GutK) is a polycyclic polyprenylated acylphloroglucinol (PPAP) isolated from Garcinia spp.Our group had previously confirmed that GutK can trigger apoptosis in colorectal cancer cells,...
Endoplasmic reticulum stress aggravation as the mechanism underlying Guttiferone K-induced apoptosis
[会议论文] 作者：Kai-kei MIU,Kenneth Kin-wah TO,Hong-xi XU,Ge LIN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Guttiferone K (GutK) is a novel cytotoxic compound able to selectively induce apoptosis in colorectal cancer cells.The study proposes endoplasmic reticulum (ER) stress aggravation as the underlyi...
Polyoxypregnanes as safe,potent,and specific ABCB1-inhibitory pro-drugs to overcome multidrug resist
[期刊论文] 作者：Wu,Chun Yin,Jiang Ma,Stella Chai,Chunyuan Zhang,Sheng Yao,Onat Kadioglu,Thomas Efferth,Yang Ye,Kenneth Kin-Wah,
来源：药学学报（英文版） 年份：2021
Multidrug resistance(MDR)mediated by ATP binding cassette subfamily B member 1(ABCB1)is significantly hindering effective cancer chemotherapy.However,currently,no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically,main......
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