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Dual inhibition of RAF/MEK/ERK and PI3K/PDK/AKT signaling pathways with small molecules as anti-canc
[会议论文] 作者：Qianbin LI,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
RAF/MEK/ERK pathways and PI3K/PDK/AKT pathways are involved in the regulation of cell growth and survival and are frequently dysregulated in human cancers,such as leukemia,melanoma and lung cancer....
Dual inhibition of RAF/MEK/ERK and PI3K/PDK/AKT signaling pathways with small molecules as anti-NSCL
[会议论文] 作者：Qianbin LI,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
The RAF/MEK/ERK and PI3K/PDK/AKT are two of the most frequently dysregulated signaling cascades in human NSCLC,which are involved in the regulation of cell growth and survival.Molecular alterations in...
[会议论文] 作者：Qianbin Li,Gaoyun Hu,Zhuo Chen,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Fibrosis is a pathological process in damaged tissues or organs where fibroblasts are activated to produce and deposit excess extracellular matrix.Accumulating evidence indicate that complicated proce...
[会议论文] 作者：Feng Liu,Liangyu Liu,Qiufang Wei,Gaoyun Hu,Qianbin Li,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
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[会议论文] 作者：Liangyu Liu,Qiufang Wei,Feng Liu,Gaoyun Hu,Qianbin Li,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Idiopathic pulmonary fibrosis(IPF)is a progressive life-threatening disease that is characterized anatomically by scarring of the lungs and symptomatically by exertional dyspnea.Currently,there is no...
[会议论文] 作者：LIANGYU LIU,XIAODING JIANG,XINLIANG YANG,LONGXING MIAO,GAOYUN HU,QIANBIN LI,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Fibrosis occurs typically as a result of inflammation or damage to obliterate the architecture and function of the underlying organs or tissues(e.g.lung,liver,heart,kidney),and finally leads to high h...
Design,synthesis and preliminary anti-lung cancer activity studies of 1,5-disubstituted-2(1H)-pyrido
[会议论文] 作者：Xin Xie,Meng Lv,Zhijun Tu,Zutao Yu,Kun Zhou,Qianbin Li,Gaoyun Hu,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
In recent years,the prevalence of lung cancer has lead to high mortality and morbidity worldwide.BMS-536924(IC50=0.1μM),one of pyridone derivatives,showed high inhibitory activity against IGF-1R kinas...
Design,Synthesis and Biological Evaluation of Novel Indol-2-one Derivatives as Anti Lung Cancer Agen
[会议论文] 作者：Juntao Ai,Zutao Yu,Meng Lv,Zhijun Tu,Kun Zhou,Gaoyun Hu,Qianbin Li,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
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Design,synthesis and preliminary anti-fibrotic activity study of 1,6-disubstituted-2(1H)-pyridone co
[会议论文] 作者：Daihong Li,Zhijun Tu,Zutao Yu,Meng Lv,Kun Zhou,Gaoyun Hu,Qianbin Li,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Idiopathic pulmonary fibrosis(IPF)is commonly considered the result of a recurrent injury to the alveolar epithelium followed by an uncontrolled proliferation of fibroblasts.Currently,there is no effi...
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