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[会议论文] 作者:Xiaojin ZHANG,Qidong YOU, 来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
Increased generation of reactive oxygen species(ROS)and an altered redox status have long been observed in cancer cells,and recent studies suggest that this biochemical property of cancer cells can be...
[会议论文] 作者:Hui Lu,Yadong Chen,Qidong You, 来源:2009长三角药物化学研讨会 年份:2009
[会议论文] 作者:Yonghua Lei,Qidong You,Xiaoj in Zhang, 来源:2016年长三角药物化学研讨会 年份:2016
Prolyl hydroxylase domain 2 (PHD2) enzyme,a FeⅡ and 2-oxoglutarate (2-OG)dependent oxygenase,which mediate key physiological responses to hypoxia by modulating the levels of hypoxia inducible factor 1...
[会议论文] 作者:Wei-lin chen,xiao-ke Guo,Qidong You, 来源:2016年长三角药物化学研讨会 年份:2016
[会议论文] 作者:Xiaoke Guo,Haopeng Sun,Qidong You, 来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
Kv1.5 potassium channel is an efficacious and safe therapeutic target for the treatment of atrial fibrillation(AF),the most common arrhythmia that threatens human.Herein,by modifying the hit compound...
[期刊论文] 作者:Lei Wang,Xiaoli Xu,Zhengyu Jiang,Qidong You, 来源:药学学报(英文版) 年份:2020
Modulation of protein fate decision and protein homeostasis plays a significant role in altering the protein level,which acts as an orientation to develop drugs...
[会议论文] 作者:Liqin Yu,Hong Su,Qidong You,Lucia Altucci, 来源:2009长三角药物化学研讨会 年份:2009
[会议论文] 作者:Dan Xu,Qi-fei Zhong,Li-ping Sun,Qidong You, 来源:2009长三角药物化学研讨会 年份:2009
[会议论文] 作者:Xiaojian Wang,Qian Yang,Qidong You,Dali Yin,Minyong Li, 来源:2009长三角药物化学研讨会 年份:2009
[会议论文] 作者:Xiaojian Wang,Qian Yang,Dali Yin,Minyong Li,Qidong You, 来源:2009长三角药物化学研讨会 年份:2009
[会议论文] 作者:Jinlian Wei,Yingrui Yang,Yali Li,Zhengyu Jiang,Qidong You, 来源:2016年长三角药物化学研讨会 年份:2016
Hypoxia-inducible factor-1 (HIF-1) as a key mediator in tumor metastasis,angiogenesis,and poor patient prognosis has been recognized as an important cancer drug target.1-4 So far,several HIF-1 inhibit...
[会议论文] 作者:Tianlin Wang[1],Qidong You[1],Hong Xiao[2],Hua Xiang[1], 来源:2009长三角药物化学研讨会 年份:2009
[会议论文] 作者:Cheng Jiang,Qidong You,Lei Yang,Mengling Chen,Fei Liu,Wutong Wu,Jiwang Chern, 来源:2008中国药学会学术年会暨第八届中国药师周 年份:2008
Based on the pharmacophore we have mapped and the binding structure of monastrol with the target protein,a series of tetrahydroisoquinolines have been identified as novel kinesin spindle protein(KSP)i...
[期刊论文] 作者:Cuicui Li,Ni Zhao,Luyan An,Zhen Dai,Xiaoyi Chen,Fan Yang,Qidong You,Bin Di,Chi Hu,Lili Xu, 来源:药学学报(英文版) 年份:2021
Lung cancers are the leading cause of cancer deaths worldwide and pose a grave threat to human life and health.Non-small cell lung cancer(NSCLC)is the most frequent malignancy occupying 80%of all lung cancer subtypes.Except for other mutatio......
[会议论文] 作者:Jinlei Bian,Xue Qian,Bang Deng,Xiaoli Xu,Xiaoke Guo,Yalou Wang,Xiang Li,Haopeng Sun,Qidong You,Xiaojin, 来源:2016年长三角药物化学研讨会 年份:2016
[会议论文] 作者:Wuchen Xie,Tongchao Liu,Jianpeng Liang,Qiang Yin,Bing Xiong,Dongmei Zhao,Qidong You,Guohua Chen,Yue-Lei, 来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
Introducing new methods for mild and stereoselective glycosylation(Scheme 1): For O-glycosides,1)Using beta-pinene as acid scavenger,direct glycosylation of taxanes was rendered possible for the first...
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