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OLIGO(ETHYLENE GLYCOL)-BASED THERMO-SENSITIVE DENDRIMERS: SYNTHESIS, DRUG LOADING AND IN VIVO BEHAVI
[会议论文] 作者:Wei Wu,Xiqun Jiang,
来源:The 6th International Symposium on Polymer Chemistry(2014年第六 年份:2014
Dendrimers possess many intriguing features,such as monodisperse and highly branched structure,globular shape,specific low-nanometer molecular size,and presence of internal cavities and abundant perip...
[会议论文] 作者:Xiqun Jiang,Jing Wang,Xu Zhen,
来源:The 6th International Symposium on Polymer Chemistry(2014年第六 年份:2014
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IN VIVO BEHAVIOR AND ANTITUMOR PERFORMANCE OF DOXCIRUBICIN-LOADED BORON-RICH POLYMERIC NANOPARTICLES
[会议论文] 作者:Wei Wu,Luzhong Zhang,Xiqun Jiang,
来源:第五届高分子化学国际学术研讨会 年份:2012
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[会议论文] 作者:Xiqun Jiang,Wei Wu,Jing Wang,Shuling Yu,
来源:The First International Symposium on Translational Nanomedic 年份:2015
Here we report an improvement in nanoparticle design to enhance drug accumulation and penetration at tumor site.We prepare a series of bovine serum albumin-poly(N-3-acrylamidophenylboronic acid)nanopa...
[会议论文] 作者:Xiqun Jiang,Wei Wu,Jing Wang,Xin Wang,
来源:第13届国际聚合物先进技术会议 年份:2015
Over past three decades,the approaches to targeting nanomaterials in vivo have been intensely explored.However,the level of antitumor agent in tumor sites i...
[会议论文] 作者:Xiqun Jiang,Jing Wang,Xin Wang,Yajun Zhang,
来源:2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 年份:2016
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[会议论文] 作者:Xiqun Jiang,Jing Wang,Xu Zhen,Xin Wang,
来源:中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议 年份:2016
Over past three decades,the approaches to targeting nanomaterials in vivo have been intensely explored.However,the level of antitumor agent in tumor sites is still low.Thus,the development of new drug...
Superior antimetastatic effect of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in a mouse metasta
[会议论文] 作者:Nannan Lu,Qin Liu,Rutian Li,Li Xie,Jie Shen,Xiaoping Qian,Lixia Yu,Yitao Ding,Wenxian Guan,Xiqun Jiang,
来源:第六届中国肿瘤内科大会 年份:2012
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Antitumor and antimetastatic effects of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in B16 beari
[会议论文] 作者:Lu,Qin Liu,Rutian Li,Li Xie,Jie Shen,Lixia Yu,Wenxian Guan,Yitao Ding,Xiaoping Qian,Baorui Liu,Xiqun Jiang,
来源:第六届中国肿瘤内科大会 年份:2012
...
Antitumor and antimetastatic effects of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in B16 beari
[会议论文] 作者:Nannan Lu,Qin Liu,Rutian Li,Li Xie,Jie Shen,Wenxian Guan,Xiaoping Qian,Lixia Yu,Yitao Ding,Xiqun Jiang,
来源:第六届中国肿瘤内科大会 年份:2012
We developed a novel pemetrexed-loaded PEG-Peptide-PCL nanoparticles.In this study, we evaluated the antitumor and antimetastasis effect of pemetrexed-loaded nanoparticles and examined the correlation...
Superior antimetastatic effect of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in a mouse metasta
[会议论文] 作者:Nannan Lu,Qin Liu,Rutian Li,Li Xie,Jie Shen,Wenxian Guan,Xiaoping Qian,Lixia Yu,Yitao Ding,Xiqun Jiang,
来源:第六届中国肿瘤内科大会 年份:2012
Using nanoparticle delivery for anticancer therapy is a potential new drug modality.We developed a novel pemetrexed-loaded PEG-Peptide-PCL nanoparticles.In this study, characterizations, drug loading...
Superior antimetastatic effect of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in a mouse metasta
[会议论文] 作者:Nannan Lu,Xiqun Jiang,Baorui Liu,Qin Liu,Rutian Li,Li Xie,Jie Shen,Wenxian Guan,Xiaoping Qian,Lixia Yu,
来源:第十五届全国临床肿瘤学大会暨2012年CSCO学术年会 年份:2012
高分子纳米抗肿瘤药物投递系统是一种新型的药物投递系统.本文介绍了一种新型的酶靶向培美曲塞纳米微球.研究了纳米微球的特征、载药量和包封率、微球的安全性和释放特性.在实验性肺转移模型中同时研究了肺转移瘤的分子表达.在四组实验组中,酶靶向培美曲塞纳米......
Antitumor and antimetastatic effects of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in B16bearin
[会议论文] 作者:Nannan Lu,Xiqun Jiang,Baorui Liu,Qin Liu,Rutian Li,Li Xie,Jie Shen,Wenxian Guan,Xiaoping Qian,Lixia Yu,
来源:第十五届全国临床肿瘤学大会暨2012年CSCO学术年会 年份:2012
本文介绍了一种新型的酶靶向培美曲塞纳米微球,在研究中,评估了这种靶向微球的抗肿瘤生长及抗肿瘤转移作业.并检测了在皮下移植瘤中E-cadherin的表达和肺转移的关系.与裸药相比,酶靶向培美曲塞纳米微球表达了最强的抗肿瘤生长及抗肿瘤转移作用,也表明E-cadherin......
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