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Suppression of Overexpression of c-Myc Gene by Chirally-Modified Polyamides Mediating Apoptosis of C
[会议论文] 作者：Xing-Lai Chen,Bing-Jia Chen,Yan-Ling Wu,Wen Zhang,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
The proto-oncogene c-Myc,a 65-kDa nuclear phosphoro-protein,is a central regulator of cellular proliferation and cell growth.The aberrant overexpression of the c-Myc gene is associated with the progre...
Endotoxin-and D-galactosamine-induced fulminant hepatic failure improved by the administration of cr
[会议论文] 作者：Li-Hua LIAN,Quan JIN,Yan-Ling WU,Ting BAI,Ji-Xing NAN,
来源：第二届世界天然药物和传统药物药理学学术会议 年份：2012
AIM Cryptotanshinone (CTN), one of the major constituents of tanshinones, was investigated for hepatoprotective effects in D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced fulminant hepatic f...
Design, Synthesis of Chiral Subunit-containing Polyamides and Their Regulation to Overexpressional P
[会议论文] 作者：Yan-Ling Wu,Dong-Long Xie,Yan-Ping Ding,Jian Gao,Wen Zhang,
来源：中国化学会第28届学术年会 年份：2012
The programmed death-1 (PD-1) molecule is an immunoreceptor,which belongs to the CD28 family and is inducibly expressed on activated T cells,NKT cells,B cells,and myeloid cells.Recent studies have sho...
Design, Synthesis of Novel oxo-heterocylic naphtalimides and Their Interaction with guanine-rich tel
[会议论文] 作者：Hong-Fei Zhang,Yi-Qian Jiang,Jia-Hua Yu,Yan-Juan Ji,Yan-Ling Wu,Wen Zhang,
来源：中国化学会第28届学术年会 年份：2012
Telomeres are significant structures at the end of chromosomes,which play an essential role in various biological events,such as aging and apoptosis.In recent years,the research on telomeres and telom...
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