GTPase相关论文
以人的胚胎cDNA为模板 ,用PCR方法筛选获得rab13基因 ,并克隆到真核表达载体pcDNA3和原核表达载体pGEX、pET 15b和 pMAL c2中 .把r......
血吸虫病是严重危害人类、牲畜健康的寄生虫病。虽然采取大规模人畜同步化疗及易感地带灭螺等措施后,血防工作取得了重大成绩,但由于......
植物叶片是植物吸收光能,进行光合作用的重要器官。植物叶器官的发育具有时间和空间上的高度特异性,是复杂的生物学过程。叶片的发育......
Ectosome-like vesicles released from the cilium/flagellum carry specific biologically-active protein
It is now well established that primary and motile cilia/flagella can act as cellular antennae,receiving signals from th......
Kinases and GTPases,the major players in cell signaling pathways,control diverse biological processes in a precisely con......
Development of embryo and endosperm display both dependent and independent programs during seed formation.In maize, ......
小G蛋白一类是低分子量GTP结合蛋白,其分子量大约20~30 kDa。小G蛋白作为重要的分子开关参与了细胞许多重要生理信号途径的调控。近......
The small GTPase Rab27 a is a member of the Rab family that is involved in membrane trafficking in various kinds of cell......
Uncontrolled high blood pressure is a major risk factor for heart attack, stroke, and kidney failure and contributes to ......
AIM:Intrahepatic extension is the main cause of liver failureand death in hepatocellular carcinoma patients.The smallGT......
以人的胚胎cDNA为模板,用PCR方法筛选获得rabl3基因,并克隆到真核表达载体pcDNA3和原核表达载体pGEX、pET-15b和pMAL-c2中.把rabl3......
The internalization of essential nutrients,lipids and receptors is a crucial process for all eukaryotic cells.Accordingl......
Objective:To investigatethesignaltransductionmechanismof gap junctionalgenesconnexin43in human cervicalcarcinogenesis.Me......
GIT1,a G-protein-coupled receptor kinase interacting protein,has been reported to be involved in neurite outgrowth.Howev......
Paralysis following spinal cord injury(SCI) is due to failure of axonal regeneration. It is believed that the capacities......
目的:预测异白花丹酮的人类疾病靶点。方法:采用Pharm Mapper在线反向对接服务器预测异白花丹酮的靶点,运用PyRx软件将异白花丹酮......
以人的胚胎cDNA为模板 ,用PCR方法筛选获得rab13基因 ,并克隆到真核表达载体pcDNA3和原核表达载体pGEX、pET 15b和 pMAL c2中 .把r......
The cycle of G-protein activation and deactivation is a key in the signaling pathway of GPCRs (G protein coupled recept......
Aim:To investigate the effect of jujuboside A(JuA)on modulating gene expres-sion in the hippocampus.Methods:The spontan......
Rho GTPase最基本的功能是结合和水解鸟嘌呤核苷酸 ,目前已从哺乳动物细胞中分离出 16种不同的 Rho GTPases,其中以 Rho、Rac和 Cd......
目的 初步探讨日本血吸虫中国大陆株pcDNA3 .1 SjRhoGTPaseDNA疫苗、重组蛋白疫苗以及联合疫苗免疫的保护机制。 方法 将 pcDNA......
Genetic and structural analyses suggest that a novel SPG3A mutation causes severe phenotypes of here
Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases. The genotypes and phenotypes of HSP are ex......
MgCdc42 (Cdc42 in Magnaporthe grisea), with high homology to ScCdc42 (Cdc42 in Saccharomyces cerevisiae), has been demon......
Salmonella enterica serovar Typhimurium encodes two type Ⅲ protein secretion/translocation systems within the pathogeni......
BACKGROUND:Rho GTPase family members have been shown to participate in neurite growth by regulating the neuronal cytoske......
目的构建携带绿色荧光蛋白的RhoA显性负效突变体(RhoAN19)和组成型活性突变体(RhoAL63)慢病毒。方法构建RhoAN19和RhoAL63慢病毒表......
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红色毛癣菌是最重要的浅表感染真菌.目前对红色毛癣菌分子和遗传学方面的研究还比较有限.应用cDNA芯片技术对红色毛癣菌不同生长阶......
Stem cells are a population of cells that has infinite or long-term self-renewal ability and can produce various kinds o......
G蛋白偶联受体激酶相互作用蛋白1/2[G-protein-coupled receptor(GPCR)kinase interacting protein 1/2,GIT1/2]属于多结构域蛋白......
雷帕霉素靶点蛋白(target of rapamycin,TOR)作为细胞内重要的生长和代谢调节中枢,主要通过形成两种复合物TORC1与TORC2发挥其功能......
The protein prenylation is one of the essential post-translational protein modifications, which extensively exists in th......
Myelination by oligodendrocytes in the central nervous system requires coordinated exocytosis and endocytosis of the maj......
Subject Code:C05With the support by the National Natural Science Foundation of China,the research team led by Prof.Gao S......
Magnaporthe Rab5 homologs show distinct functions in nerve growth factor(NGF)-mediated neurite outgr
Nerve growth factor(NGF) binds to TrkA and forms a NGF/TrkA complex at the cell surface,which is then internalized into ......
RhoGAPs(GTPase activating proteins)通过与Rho GTP酶结合,促使GTP酶水解成Rho GDP无活状态,在生物体中调控着重要的生物学功能。......
Neurofibromatosis type 1 is a common autosomal dominant disorder with a high rate of penetrance. It is caused by the mut......
作为中枢神经,视神经与脊髓不同,它是由视神经节细胞的轴索和视神经胶质组成,没有神经元胞体等成分,也就是说由白质构成.Crutcher......
目的:探讨G3BP(Ras-GTPase-activiting protein SH3 domain binding protein)在结肠癌组织中的表达及其临床病理意义。方法:用免疫......
Regulation of deleted in liver cancer-1 gene domains on the proliferation of human colon cancer HT29
Objective To study the role of deleted in liver cancer-1(DLC-1) gene main domains on the regulation of hu-man colon canc......
用酿酒酵母(Saccharyomyces cerevisae)ScGSP1蛋白基因从COGEME植物病原菌EST库中BLAST得到栗疫病菌的GSP1蛋白EST,设计引物从栗疫......
Molecular docking studies of anti-cancerous candidates in Hippophae rhamnoides and Hippophae salicif
Actinorhizal plants contain numerous antioxidants that may play a crucial role in preventing the formation of tumors.H-R......
Ras相关GTP酶超家族包括约150个小单体鸟嘌呤核苷酸结合蛋白成员,主要包括5个亚家族:Rho、Ras、Rab、Arf/Sar和Ran[1]。Rho家族蛋......
AIM:To determine how the oncogene mi R-21 regulates the RAS signaling pathways and affects colon cancer cell behaviors.M......