Hypoxia-inducible相关论文
Endogenous reactive oxygen species and nitric oxide have opposite roles in regulating HIF-1alpha exp
Ischemic stroke results in cerebral tissue hypoxia and increased expression of hypoxia-inducible factor(HIF),which is cr......
Objective: α-ketoglutarate(α-KG) is the substrate to hydroxylate collagen and hypoxia-inducible factor-1α(HIF-1α), w......
目的：检测HIF－1a、Endoglin和sEng在子痫前期患者胎盘及血清中的表达，并探讨他们在子痫前期发病机制中的作用。方法：选择子痫前期病人3......
,Hidden secret in hepatitis B viral X protein mutation and hypoxia-inducible factor-1α in hepatocarc
Hepatitis B type virus (HBV) is an old hepato oncogenic and hepatitis agent. Hepatitis B viral X protein (HBx)-induced m......
目的探讨低氧诱导因子-1α(HIF-1α)在大鼠肝肺综合征(HPS)发病中的作用及其与糖调节蛋白78(GRP78)的关系。方法复合致病因素法制......
目的 探讨缺氧诱导因子-1α(hypoxia-inducible factor-1α,HIF- 1α)在早产儿视网膜病发病中的作用,为其基因治疗寻找新的靶点.方......
Hypoxia-inducible factor-1α–mediated upregulation of CD99 promotes the proliferation of placental me
BACKGROUND As human placenta-derived mesenchymal stem cells(hP-MSCs)exist in a physiologically hypoxic microenvironment,......
Expression and Clinical Significance of Hypoxia-related Factors HIF-1a,Gli-1 and MMP9 in Breast Canc
Objective:To investigate the expression and clinical significance of hypoxia inducible factors HIF-1a,Gli-1 and MMP9 in ......
目的：探讨RNAi靶向沉默人鼻咽癌细胞株CNE-2细胞缺氧诱导因子-1α（HIF-1α）和/或生存素（Survivin）基因对裸鼠移植瘤放疗敏感性的影响。......
AIM:To investigate the association between hypoxiainducible factor-1α(HIF-1α) polymorphisms(-1772C>T and-1790G>A) and ......
Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carci
AIM: To investigate the influence of phosphatidylinositol-3-kinase protein kinase B(PI3K/AKT)-HIF-1α signaling pathway ......
目的探讨缺氧诱导因子-1α(HIF-1α)、缺血修饰白蛋白(IMA)水平对射血分数正常心力衰竭患者的预后评估价值。方法选取2018年6月至2......
Background Increasing research suggests that mitochondrial defect plays a major role in pulmonary hypertension(PH) patho......
目的分析缺氧诱导因子-1α（HIF-1α）在喉鳞状细胞癌中的表达及与微血管密度（MVD）的关系,探讨其与喉癌生物学行为及预后的关系。方法采......
Is the hypoxia-inducible factor-1 alpha mRNA expression activated by ethanol-induced injury, the mec
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AIM: To investigate the expression of CD73 and hypoxia-inducible factor-1α (HIF-1α) in human gastric carcinoma, and ex......
AIM:To study the effects of hypoxia-inducible factor1α(HIF-1α) silencing on the proliferation of hypoxic CBRH-7919 rat......
The liver is a central organ that metabolizes excessive nutrients for storage in the form of glycogen and lipids and sup......
BACKGROUND Gastric cancer (GC) is one of the main causes of cancer mortality worldwide. Recent studies on tumor microenv......
目的：验证生理性骨骼肌缺血训练上调血管内皮生长因子（vascular endothelial growth factor,VEFG）的表达与骨骼肌局部缺血产生的缺氧......
目的探讨雷帕霉素对视网膜缺血-再灌注损伤（retinal ischemia-reperfusion iniury，RIRI）的保护作用和机制。方法75只SPF级健康雄性Wis......
目的：观察曲古抑菌素A（TSA）体外对结肠癌HT-29细胞凋亡及低氧状态下其缺氧诱导因子（HIF）-lα表达的影响。方法：体外培养结肠癌HT-29细胞，......
骨关节炎是临床常见病、多发病,其重要始发因素及病理改变是软骨退变。软骨组织处于低氧微环境中,低氧诱导因子1α（hypoxia-inducib......
目的 探讨shRNA特异性干扰沉默缺氧诱导因子-1α（HIF-1α）对类风湿关节炎（RA）成纤维样滑膜细胞（FLS）的血管内皮生长因子（VEGF）表达及其增殖......
目的：探讨缺氧诱导因子-1α（ hypoxia-inducible factor-1α,HIF-1α）及促红细胞生成素（ erythropoietin,EPO）在碱烧伤大鼠角膜组织中的......
目的：探讨缺氧诱导因子-1α（ HIF-1α）和CD44 v6在甲状腺乳头状癌中的表达及其临床意义。方法应用免疫组织化学SP法检测140例乳头状癌......
研究肿瘤血管的生成机制,探索抑制肿瘤血管的生成,可以为肿瘤的预防、诊断和治疗方法的改进提供新的理论支持.环加氧酶（COX）2的过表......
目的观察老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者低氧诱导因子-1(HIF-1)和脑红蛋白(Ngb)水平变化,分析其在老年OSAHS患者......
目的：研究分析急性脑出血患者血清低氧诱导因子（hypoxia-inducible factor-1α，HIF-1α）与血管生长因子（vascular endothelial growth f......
目的探讨缺氧诱导因子-1α（HIF-1α）及胰岛素样生长因子-2（IGF-2）在宫颈癌（ICC）发生、发展中表达及意义。方法应用免疫组织化学S-P方法,......
HIF-2αregulates CD44 to promote cancer stem cell activation in triple-negative breast cancer via PI3
BACKGROUND Breast cancer is a common malignant tumor that seriously threatens women’s health.Breast cancer stem cell(CS......
目的研究乳腺癌组织中VHL、HIF-1α和HIF-1αmRNA的表达及VHL对后两者的影响,并探讨其意义。方法制作80例乳腺癌组织芯片,另设20例......
Hepatocellular carcinoma(HCC) is one of the most commonly diagnosed and deadly cancers worldwide; its incidence has been......
目的 探讨曲安奈德(TA)对体外缺氧培养的人视网膜色素上皮(RPE)细胞缺氧诱导因子1α(HIF-1α)及血管内皮生长因子(VEGF)合成的影响......
目的：探讨食管鳞癌细胞中缺氧诱导因子-1α（HIF-1α基因与食管鳞癌细胞增殖活力和细胞周期的关系。方法：以RNA干扰方法构建出HIF-1α......
CITED2(CBP/p300-interacting transactivator with Glu/Asp-rich C-terminal domain,2)is a ubiquitously expressed protein exh......
AIM To investigate the roles and interactions of mutThomolog （MTH）-1 and hypoxia-inducible factor （HIF）-1αin human colorect......
An inhibitor of HIF-αsubunit expression suppresses hypoxiainduced dedifferentiation of human NSCLC i
ferentiation of non-small cell lung cancer(NSCLC)cells and whether a hypoxia-inducible factor(HIF)inhibitor is able to s......
Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellu
BACKGROUND Hypoxia-inducible factor 1α(HIF-1α) is a gene that regulates tumor survival,neovascularization and invasion......
AIM:To study the expression of carbonic anhydrase(CA)9 in human hepatocellular carcinoma(HCC)cells.METHODS:We studied CA......
HIF-1α expression in keloid and its correlation with angiogenesis, inflammatory response and apoptos
Objective:To study the expression of hypoxia-inducible factor-1α (HIF-1α) in keloid and its correlation with angiogene......
Aim: Shigella flexneri (S. flexneri) is a gram-negative enterobacterium responsible for severe intestinal end systemic i......
The timing and extent of intraosseous hypoxia in the oxidative stress-induced rat osteonecrosis mode
Using a rat oxidative stress-induced femoral head osteonecrosis model, we determined the presence/ absence and timing of......
Background:Exercise induces blood flow redistribution among tissues,leading to splanchnic hypoperfusion.Intestinal epith......
