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The affect and regulatory mechanisms of PARP-1 inhibitors on the radiosensitivity of brca mutant bre
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目的 观察沙立度胺对人乳腺癌细胞系MCF-7、MDA-MB-231细胞血管内皮生长因子(VEGF)表达的抑制作用.方法 应用半定量逆转录-聚合酶......
目的探讨微小RNA-22(miRNA-22)在食管癌及胃癌组织和细胞株中的表达及临床意义。方法采用实时定量PCR法分别检测人食管癌细胞系ECA......
The study of chemiluminescence in gastric and colonic carcinoma cell lines treated by anti-tumor dru
AIM: To study the influence of chemotherapy on proliferationactivation of tumor cell by observing the change ofchemilumi......
Mutation analysis of novel human liver-related putative tumor suppressor gene in hepatocellular carc
AIM: To find the point mutations meaningful for inactivationof liver-related putative tumor suppressor gene (LPTS) gene,......
AIM: To investigate the effects of p16 gene on biologicalbehavious in hepatocellular carcinoma cells.METHODS: HCC cell l......
The effect of adenovirus expressing wild-type p53 on 5-fiuorouracil chemosensitivity is related to p
AIM: There are conflicting data about p53 function on cellular sensitivity to the cytotoxic action of 5-fluorouracil (5-......
Construction of exogenous multiple epitopes of helper T lymphocytes and DNA immunization of its chim
AIM: To design and construct an exogenous multiple epitope of helper T lymphocytes (HTL), and to evaluate its effect on ......
AIM: To explore the role of hepatitis C virus (HCV) envelope protein 2 (E2) in the induction of apoptosis.METHODS: A car......
AIM: To investigate the effect of histone acetylation on regulation of p21WAF1 gene expression in human colon cancer cel......
Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apopto
AIM: To investigate the relations between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Helicobact......
Construction and selection of subtracted cDNA library of mouse hepatocarcinoma cell lines with diffe
AIM: In order to elucidate the molecular mechanism of lymphatic metastasis of hepatocarcinoma, we detected the differenc......
AIM: To investigate the modification of baculovirus vector and the feasibility of delivering exogenous genes into mammal......
Structure analysis and expressions of a novel tetratransmembrane protein, lysosoma-associated protei
AIM: To analyze the structure and expressions of the protein encoded by an HCC-associated novel gene, lysosomeassociated......
Alterations in expression, proteolysis and intracellular localizations of clusterin in esophageal sq
AIM: To investigate biogenesis and intracellular localizations of clusterin to elucidate the potential molecular mechani......
AIM: To detect the thymidine phosphorylase (dThdPase)expression in human colorectal cancer tissues and cells.METHODS: Fo......
AIM: To study the anti-neoplastic effect of Haimiding and its mechanisms of action.METHODS: Experiments using MTT and co......
Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase wit
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AIM: To study the effect of red oil A5 on pancreatic cancer cells and its possible mechanisms.METHODS: Effect of differe......
Recombinant hybrid protein, Shiga toxin and granulocyte macrophage colony stimulating factor effecti
AIM: To investigate the selective cytotoxic effect of constructed hybrid protein on cells expressing granulocyte macroph......
Mechanism of apoptotic effects induced selectively by ursodeoxycholic acid on human hepatoma cell li
AIM: To investigate the effects of ursodeoxycholic acid(UDCA) on apoptosis and proliferation of hepatoma celllines.METHO......
In vitro antiproliferative and apoptosis inducing effect of a methanolic extract of Azadirachta indi
Objective: To find the cytotoxic and apoptotic effects of neem oil extract on the selected cancerous (A-549, PC-3 and DU......