costimulation相关论文
Augmented Cytokine-induced Killer Cells Cultured With Engineered Cells for Costimulatory Enhancement
Objective: Cytokine-induced killer cells(CIKs)were shown to be a promising tool in the quest for new therapeutic approac......
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The past years have witnessed significant advance in our understanding of critical roles of T cell co-signals in B7-CD28......
T细胞上可诱导表达的,与单纯疱疹病毒( HSV )的糖蛋白 D 竞争结合 HSV 侵入介导物(HVEM)的淋巴毒素类似物(LIGHT)是肿瘤坏死因子超家族的......
CD4+T细胞是HIV-1感染和破坏的最重要靶细胞.在自然感染和通常的实验体系中,CD4+T细胞的活化和增殖是HIV-1得以大量繁殖和广泛播散......
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Interactions Between TLR7 and TLR9 Agonists and Receptors Regulate Innate Immune Responses by Astroc
Toll样受体7(TLR7)和Toll样受体9(TLR9)是固有免疫反应中的重要介质.它们均定位于内涵体间隔,识别核酸和经过髓样分化因子88(MyD88......
Vascular cell adhesion molecule 1 (VCAM-1) is a member of immunoglobulin superfamily. The principal ligand for VCAM-1 is......
本研究观察不同的细胞刺激因子共刺激对人CIK细胞增殖和功能的影响.用淋巴细胞分离液分离人外周血单个核细胞(PBMNC),按常规方法从......
Ligation of T cell receptor (TCR) alone is insufficient to induce full activation of T lymphocytes. Additional ligand-re......
研究共刺激信号在肿瘤免疫中的作用.脂质体介导DNA转移法将人B7基因转入人肝癌细胞株Smmc7721,建立新的细胞株B7+Smmc7721,PCR及逆......
目的 探讨T细胞共刺激分子B7-1、CD40和CD54在Graves病(GD)患者甲状腺组织中的表达及其发病机制.方法采用免疫组织化学方法(HRP)观......
【正】 OBJECTIVE: To study the function of costimulation sign in tumor immunology and construct the new cellline B7~+ Sm......
B7家族属免疫球蛋白类,目前已发现5种,即B7-1,B7-2,B7-H1,B7-H2和B7-H3等。它们结构相似,均可在机体免疫过程中作为共刺激因子(第2信号),与T、B细......
CD4记忆T细胞在保护机体免受病毒、细菌、寄生虫等物质感染中起十分重要的作用,并与自身免疫反应、变态反应等有关异常的免疫反应......
目的:探讨CD3/CD46共刺激通路对同种移植免疫反应的调控作用及其机制。方法:分离转人CD46的C57BL/6小鼠的脾脏淋巴细胞,采用MACS免疫......
目的:研究共刺激信号在抗肝脏肿瘤免疫中作用.方法:分析经anti-CD3McAb和anti-CD28McAb协同共刺激,并与肝脏肿瘤细胞(HepG2-2215细......
血管细胞粘附分子-1是一种属于免疫球蛋白超家庭成员的细胞粘附分子,其配体主要是整合素家族的α4β1/VLA-4。近年来发现VCAM-1亦在巨噬细胞,树突状细......
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目的探讨干预CD86协同刺激信号对母胎界面Th1/Th2型细胞因子转录调控及妊娠结局的影响.方法:将正常妊娠模型(CBA/J×BALB/c)和......
The plasticity and dynamism in the immune responses to both self and environmental stimulation promote the maintenance a......