ALDOSE相关论文
多年来,全世界都在研究糖尿病及其各种慢性并发症的发病机理、寻找有效的防治途径。近十年来,随着对多元醇代谢通路认识的深入,应......
近年研究表明,应用醛糖还原酶抑制剂可以预防和治疗糖尿病慢性并发症。本文详述了醛糖还原酶抑制剂的种类和基本作用;糖尿病慢性并......
本文简述醛糖还原酶和多元醇通路与糖尿病慢性并发症的关系;对醛糖还原酶抑制剂治疗和预防糖尿病慢性并发症的作用进行评估,并介绍......
Evaluation of in vitro aldose reductase inhibitory potential of different fraction of Hybanthus enne
Objective:To evaluate the aldose reductase inhibitory(ARI)activity of different fractions of Hybanthus enneaspermus for ......
Epalrestat protects against diabetic peripheral neuropathy by alleviating oxidative stress and inhib
Epalrestat is a noncompetitive and reversible aldose reductase inhibitor used for the treatment of diabetic neuropathy. ......
AIM:Myocardial fibrosis induced by activated cardiac fibroblasts(CFs)is thought to play a key role in the pathogenesis o......
AIM:To prepare and characterize polyclonal antibodiesagainst aldose reductase-like (ARL-1) protein.METHODS:ARL-1 gene w......
醛糖还原酶相似基因(aldose re-ductase-like gene,ARL-1)表达的增高与肝癌抗药性关系的研究是近年来发展的一个新课题。曹德良等[......
目的:观察灯盏细辛等8种中药对人醛糖还原酶(aldose reductase,AR)活性的影响。方法:在体外模型下用酶法对8种中药的AR活性抑制率......
Objective:To assesse the inhibitor) effect of alcoholic extract of two Indian medicinal plants namely Ceasalpinia digyna......
Aldose reductase (AR), a cytosolic, monomeric oxidoreductase, is a key enzyme in the polyol pathway which controls the c......
The formation of advanced glycation end-products(AGEs) and aldose reductase(AR) activity have been implicated in the dev......
Aim: To investigate the preventive and protective effects of bendazac lysine (BDL) on experimental early diabetic nephr......
半乳糖激酶(galactokinase,GK)是催化半乳糖代谢的关键酶。当其活性降低或缺乏时,体内蓄积的半乳糖可被醛糖还原酶(aldose reduct......
A new coumestan, 3, 9-dihydroxy-4, 8-dimethoxycoumestan, was isolated from Arachis hypogaea L. together with two known c......
一系列 Benzisolselenazolone (BISA ) 衍生物为他们的抗菌剂活动 againstE coli 被综合并且评估。由使用 LKB-2277 bioactivity ......
Fatty liver disease(FLD) is a growing public health problem worldwide. There is an urgent requirement for alternative an......
本文以鼠李糖和对氨基苯甲酸为原料合成了抗癌新药Ｋ－ＡＭ，并作了红外鉴定。...
目的观察葛根素对D-半乳糖（D-gal）诱导大鼠体内蛋白非酶糖基化反应、胰岛素抵抗、糖耐量和醛糖还原酶（AR）活性的作用。方法除空白对照......
目的:探讨染色体7q35区醛糖还原酶(AR)基因启动子区C-106T多态性与中国北方汉族人2型糖尿病肾病(DN)的相关性. 方法:运用聚合酶链......
Evaluation of in vitro aldose reductase inhibitory potential of different fraction of Hybanthus enne
Objective:To evaluate the aldose reductase inhibitory（ARI）activity of different fractions of Hybanthus enneaspermus for po......
[Objectives] To explore whether there are natural substances that inhibit human aldose reductase in different extracts o......
To investigate the therapeutic potentials of na- tural sources, stepwise polarity fractions of Blumea balsamifera were t......
Inhibition Effects of Salvianolic Acid M and Rosmarinic Acid in Salvia deserta Schang on Human Aldos
[Objectives]This study aimed to investigate the inhibition effects of two chemical constituents in Salvia deserta Schang......
