Alzhei相关论文
Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mou
Graphical Abstract Abstract Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural plasticity......
目的评价脑脊液总tau(t-tau)蛋白和磷酸化tau(p-tau)蛋白预测轻度认知障碍(MCI)患者进展为阿尔茨海默病(AD)的临床价值。方法全面......
Multifractal analysis of white matter structural changes on 3D magnetic resonance imaging between no
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为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Cognitive function in the elderly is affected by various environmental,social,and individual factors.Studies show that c......
中医认为，AD发病的关键是肾精虚损为本，导致痰瘀闭窍，临床上以补肾益气、活血解毒中药组成小复方取得较好的疗效。本文以多种动物模型......
To reveal the relationship between mitogen-activated protein kinase (MAPK) and tau phosphorylation, we used different co......
目的:评价延续护理的综合评估在德州市阿尔茨海默病患者中的应用效果.方法:将84例老年痴呆患者按照入院时间分为对照组44例和观察......
目的构建II型糖尿病（T2D）合并阿尔兹海默症（AD）的小鼠模型。方法选取雄性（APP／PS1^＋＋／dbMb^＋／＋）小鼠和雌性（APP／PS1-/-／db^＋/-）小鼠进行杂交；选取子代......
目的：研究组织蛋白酶B（Cathepsin B,CB）与β-淀粉样蛋白（β-amyloid protein,Aβ）激活星形胶质细胞诱导炎性反应的关系。方法：应用免疫细......
中国全科医学杂志与澳大利亚Monash大学和Melbourne大学的全科医学专家和心理学专家在2012年伊始共同推出“全科医学中的心理健康......
目的:研究电针联合音乐疗法对轻中度阿尔茨海默病患者认知功能和日常生活活动能力的影响。方法:选取2015年1月至2017年8月张家口市......
目的:观察抗氧化剂TA9901对注入脑内的β-淀粉样蛋白1-40(Aβ1-40)纤维形成的干预作用,以进一步研究其治疗老年性痴呆(AD)的作用机......
目的： 探讨阿尔茨海默病（AD） 模型大鼠学习记忆能力与脑组织β淀粉样蛋白（amyloid β-protein，Aβ）之间的关系。方法： 选用雄性Wistar大鼠......
轻度认知功能障碍(MCI)目前已经成为严重影响老年人健康的疾病,早期具有可逆性。近年来弥散张量成像(DTI)以其定量显示脑白质纤维......
胰高血糖素样多肽l（Glucagon-like peptide，GLP）已被证明是有前景的Ⅱ型糖尿病（Type 2 diabetes mellitus，T2DM）治疗剂。阿尔茨海默病（Alz......
活化T细胞核因子（nuclear factor of activated Tcell,NFAT）是具有多向调节功能的转录因子,如调节T细胞的活化、分化及自身耐受性等......
目的探讨香港远志提取物对拟阿尔茨海默病（AD）模型大鼠学习记忆能力的影响及机制。方法SD大鼠随机分4组：假手术组、模型组及治疗A、B......
目的:提出一种基于脑MRI与深度学习和迁移学习准确区分阿尔茨海默病(Alzheimer'sdisease,AD)与正常老化(normalcontrol,NC)的......
Tau is an intracellular protein,found mainly in neurons,but it can also be found in the extracellular space in pathologi......
Mesenchymal stem cell-derived exosomes promote neurogenesis and cognitive function recovery in a mou
Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural plasticity and improve cognitive impai......
Cognitive and Functional Profiles in Mild-to-Moderate Alzheimer’s Disease and Mild Cognitive Impairm
Background: Amnestic mild cognitive impairment (aMCI) and mild-to-moderate Alzheimer’s disease (AD) are clinically dist......
Homocysteine and asymmetric dimethylarginine concentrations in the plasma of Alzheimer’s disease pat
Alzheimer’s disease (AD) is accompanied by elevated levels of homocysteine (Hcy). Homocysteine may induce elevated conc......
γ-Secretase is involved in the final processing of the amyloid precursor protein into a heterogeneous pool of β-amyloi......
