GERMLINE相关论文
...
Inherited Genetic Susceptibility to Nonimmunosuppressed Epstein-Barr Virus-associated T/NK-cell Lymp
Epstein-Barr virus(EBV)T/NK-cell lymphoproliferative diseases are characterized by clonal expansion of EBV-infected T or......
目的研究1个家族性腺瘤性息肉病家系的腺瘤样息肉病基因（adenomatous polyposis coli，APC）的胚系突变。方法经结肠镜、组织病理学检查......
Two novel germline mutations of MLH1 and investigation of their pathobiology in hereditary non-polyp
...
MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorect
AIM:To detect the MLH1 gene promoter germlinemethylation in probands of Chinese hereditary nonpolyposis colorectal cance......
Germline genomes have a dominant-heritable contribution to cancer immune evasion and immunotherapy r
Background: Immune evasion is a fundamental hallmark for cancer.At the early stages of tumor development,immune evasion ......
Maize is the most important agricultural crop used for food,feed,and biofuel as well as a raw material for industrial pr......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
GATA-2,a transcription factor,is expressed in several types of blood cells and in the central nervous system (CNS),and r......
MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorect
AIM:To detect the MLH1 gene promoter germlinemethylation in probands of Chinese hereditary nonpolyposis colorectal cance......
小RNAs可以在转录和转录后水平沉默转座子，最近发现的几类小RNAs（piRNAs、endo—siRNAs）均具有抑制转座子活性的作用，其中，果蝇piRNAs、......
AIM:To give a comprehensive report of E-cadheringene （CDH1） variations in a population at a high risk for gastric cancer （G......
前列腺癌的侵袭性是否有遗传因素还是一个谜题，但是DNA分析技术的发展肯定会在将来解开这一谜题的。......
AIM： To explore germline hypermethylation of the tumor suppressor genes MLH1, CDH1 and P16INK4a in suspected cases of her......
Prevalence and clinical significance of pathogenic germline BRCA1/2 mutations in Chinese non-small c
Objective: Germline alterations in the breast cancer susceptibility genes type 1 and 2, BRCA1 and BRCA2, predispose indi......
In mice,gene targeting by homologous recombination continues to play an essential role in the understanding of functiona......
The field of reproductive biology has undergone significantdevelopments in the last decade. The notion thatthere is a fi......
Pluripotent stem cells are unspecialized cells withunlimited self-renewal, and they can be triggered todifferentiate int......
BACKGROUND Identification of germ-line mutations in pancreatic ductal adenocarcinoma(PDAC)could impact on patient/family......
Imatinib response of gastrointestinal stromal tumor patients with germline mutation on KIT exon 13:A
Familial gastrointestinal stromal tumor(GIST) is a rare autosomal dominant disorder associated with mutations in the KIT......
前列腺的正常、肿瘤的生长开是依赖的雄激素受体(AR ) 表示和功能。与它的 coregulatory 因素联合， AR 的 Androgenic 激活是导致 A......
Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial ca
Objective:Lynch syndrome(LS)predisposes patients to early onset endometrioid endometrial cancer(EEC).However,little is k......
BACKGROUND Genetic testing is widely recommended for all epithelial ovarian cancer(EOC)patients.However,an increased pro......
The conditional mutations in D. melanogaster are produced by gamma-irradiation, maintained in laboratory cultures, and i......
