GLYCOPROTEINS相关论文
糖基化是蛋白质翻译后修饰的重要形式之一，糖蛋白的糖链在细胞识别、细胞间信号传递、细胞迁移、增殖及分化中均具有重要作用，唾液酸......
原发性肝癌是我国第4位常见恶性肿瘤及第2位肿瘤致死病因，研发新型生物标志物应用于肝癌患者的早诊早治对于提高生存率十分重要。目......
血小板表面具有丰富的糖萼，血小板糖基化在生理止血机制中发挥重要作用，调节血小板与受体蛋白相互作用，并通过自身糖代谢系统动态重塑......
Application of magnetic solid phase extraction in separation and enrichment of glycoproteins and gly
The analysis of endogenous glycoproteins and glycopeptides in human body fluids is of great importance for screening and......
Genome Characteristics and Evolution of Pseudorabies Virus Strains in Eastern China from 2017 to 201
Since late 2011,outbreaks of pseudorabies virus (PRV) have occurred in southern China causing major economic losses to t......
Force mapping of physiological surfaces, gels and structures: high resolution determination of biolo
The nanoscale characterisation of soft biological surfaces in aqueous environments remains challenging.We have developed......
identification and verification of candidate biomarkers in the tissues of colon cancer patients by g
In order to discover potential glycoprotein biomarkers in colon cancer, we used microarray and MS analysis approach.In t......
Enrichment of GalNAz labled-glycoproteins by Novel Disulfideand Terminal Alkyne-modified Magnetic Be
Glycosylation is one of the most significant and widespread posttranslational modification of proteins.The change of gly......
Molecularly Imprinted Polymer-based Plasmonic Immunosandwich Assay:An Appealing Alternative to Immun
Glycoproteins being vital in numerous biological processes are considered as important targets for many clinical diagnos......
Boronate affinity molecularly imprinted polymers combined with surface enhanced Raman Scattering(SER
Glycoproteins play essential roles in many biological processes,such as molecularrecognition,inter-and intracellular sig......
A novel thiol grapheme(TG)functionalized poly[ionic liquid(ViOcIm+Cl-)] boronate affinity monolithic column was prepared......
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Ebola virus (EBOV), a member of the filovirus family, is an enveloped negative-sense RNA virus that causes lethal infect......
Boronate affinity monolithic capillary-based rapid selection of high-specificity glycoprotein-bindin
Aptamers are oligonucleic acids or peptides that can specifically bind a target molecule.Aptamers are usually select......
目的 探讨胆汁糖蛋白糖链结构变化对于鉴别良恶性胆道疾病的作用。方法选取青岛市海慈医疗集团普外科收治的胆道疾病患者100例，按照......
目的研究原发性肝癌介入治疗前后DKK1表达水平的变化及其临床意义。方法选取原发性肝癌患者120例（研究组），另选取健康体检者120例（对照......
目的 观察氟对小鼠骨组织白细胞介素-6 (IL-6)、糖蛋白130(gp130)、磷脂酰肌醇3-激酶(PI3K)、蛋白激酶B(Akt)表达的影响,探讨IL-6/......
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[目的]探讨维持性血液透析(Hemodialysis,HD)患者锌α2糖蛋白(zinc-α2-glycoprotein,ZAG)的表达及其意义.[方法]选择维持性HD患者......
蛋白糖基化一度被认为只存在于真核生物中,但近年越来越多的研究显示,无论是N-连接糖基化还是O-连接糖基化都同样存在于原核微生物......
Wnt pathway in the formation of ischemic brain injury Interventional pathway of basic fibroblast gro
BACKGROUND: Basic fibroblast growth factor (bFGF) can reduce neuronal apoptosis following ischemia/reperfusion (I/R) inj......
,Glycosylation on proteins of the intestine and perimicrovillar membrane of Triatoma (Meccus) pallid
Trypanosoma cruzi,the causative agent of Chagas disease,interacts with molecules in the midgut of its insect vector to m......
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Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Wnt pathway in the formation of ischemic brain injury Interventional pathway of basic fibroblast gro
BACKGROUND: Basic fibroblast growth factor (bFGF) can reduce neuronal apoptosis following ischemia/reperfusion (I/R) inj......
目的 检测人牙周韧带细胞(periodontal ligament stem cell,PDLC)诱导矿化过程中碱性磷酸酶(alkaline phosphatase,ALP)、骨钙素(o......
目的探讨分化型甲状腺癌（DTC）手术及^131Ⅰ清除剩余甲状腺组织（清甲）后复发时^99Tc^m-甲氧基异丁基异腈（MIBI）显像的特点及耐药蛋白（P-糖......
目的 用99Tcm-甲氧基异丁基异腈(MIBI)细胞摄取变化探测肿瘤细胞P.糖蛋白(P-gP)表达及多药耐药(MDR)逆转剂存在时P-gP功能的变化.......
目的 探讨高尔基体糖蛋白73 (GP73)在不同人群中的检测水平和范围. 方法 在启东某社区35 ～ 69岁人群中,用HBsAg检测筛查12378人,随......
Syringic acid, a novel natural phenolic acid, normalizes hyperglycemia with special reference to gly
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Epstein-Barr virus(EBV) infection occurs by distinct mechanisms across different cell types. EBV infection of B cells in......
目的 分析我国近期分离的6株代表性狂犬病病毒(rabies virus,RV)的糖(G)蛋白基因序列,了解RV街毒株与疫苗株在核苷酸和氨基酸序列......
目的建立抗水痘-带状疱疹病毒(varicella zoster virus，VZV)抗体的VZV糖蛋白(glycoprotein，gp)ELISA(VZVgp ELISA)，提高抗VZV抗体的检......
单纯疱疹病毒(herpes simplex virus,HSV)2型是一种主要引起生殖器疱疹的病原体,它可以在宿主体内终身潜伏并增加人们感染HIV的几......
目的 探讨白细胞介素-11(IL-11)及可溶性糖蛋白130(sgpl30)在初诊急性白血病(AL)诱导缓解过程中的变化及临床意义.方法 采用ELISA......
人巨细胞病毒( human cytomegalovirus,HCMV)普遍存在于各类人群中,是先天性病毒感染的最常见原因.近年来HCMV疫苗的研制取得了巨......
富含半胱氨酸的酸性分泌糖蛋白是纤维化疾病进程中的一个关键因素.体内外实验表明,其能影响多种细胞的活动,富含半胱氨酸的酸性分......
目的评价行肝动脉栓塞化疗术（TACE）的原发性肝癌患者手术前后血清高尔基体蛋白73（GP73）的动态变化及其临床意义；探讨肝癌患者血清GP73与......
Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma
INTRODUCTIONDevelopment of drug-resistance to chemotherapyand subsequent metastasis of tumor are primarilyresponsible fo......
目的 探讨尼洛替尼、5-溴汉防己甲素(BrTet)及其联合应用对K562/A02细胞多药耐药的逆转作用及其机制.方法 尼洛替尼、BrTet单独或......
目的 初步了解兔椎间盘不同成分的免疫源性差别,进一步提示人体内不同椎间盘细胞的抗原性差别.方法 根据生物基因相似性原理及在椎......
目的 了解正己烷对人体血清髓鞘P0蛋白抗体与P2蛋白抗体表达的影响.方法 选取接触正己烷1年以上的工人269名作为接触组,同时选取未......
目的 评价P-糖蛋白(P-gp)表达对癌痛病人芬太尼或氯诺昔康镇痛效果的影响.方法 癌痛病人100例,年龄的49～64岁,体重55～65 kg,其中肿瘤......
目的 研究乌司他丁(UTI)对实验性自身免疫性脑脊髓炎(EAE)髓鞘再生及脑源性神经营养因子(BDNF)表达的影响.方法 24只C57BIZ6雌性......
YKL-40（人软骨糖蛋白-39）是一种新发现的炎性因子，属于哺乳动物18-糖基水解酶家族成员。既往研究表明，YKL-40与急慢性炎症性疾病和肿瘤......
AIM: To estimate the serum α1-antichymotrypsin (ACT),α1-acid glycoprotein (AGP) and transferrin (Tf) concentrations an......
目的分析鉴定与肝细胞癌(HCC)发生发展相关的差异表达的N-连接糖蛋白。方法应用刀豆蛋白凝集素(ConA)、晶状体凝集素(LCH)和雪花凝......
顺铂被广泛应用于肺癌的临床化疗,但耐药性的产生严重影响其疗效.顺铂耐药的机制尚不十分清楚.目前普遍认为P-糖蛋白(P-gp)的表达......
开展个性化精准医疗的核心在于对复杂生物样本进行个性化表征.糖链大量存在于人体组织、细胞和各类体液蛋白表面,发挥重要生物功能......
