Incretin相关论文
2型糖尿病是21世纪慢性病防治的巨大挑战之一。良好的血糖控制可以避免或延缓大血管及微血管并发症的发生及进展。基于肠促胰岛素......
肠促胰素是经食物刺激后由肠道细胞分泌入血、具有促进胰岛素分泌作用的一类激素;人体中,胰升糖素样肽1(GLP-1)和糖依赖性胰岛素释......
Detection of serum iron and zinc levels in patients with type 2 diabetes mellitus and their relation
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
基于肠促胰素特别是胰高血糖素样肽(GLP)-1类似物的治疗方法,针对2型糖尿病的多个病理生理靶点,单药治疗和联合用药均显示出良好的......
肠促胰素(incretin)是一类在食物营养物质刺激下,由肠道内分泌细胞合成分泌的激素,具有葡萄糖依赖性促胰岛素分泌的特性,可通过促......
近年来在2型糖尿病发病机制及治疗领域研究中,肠促胰素是一大突破.本文以肠促胰素分泌生理机制、病理变化到临床应用为线索,简要介......
肠促胰素是经食物刺激后由肠道细胞分泌入血、能够刺激胰岛素分泌的一类激素.人体中,胰升糖素样肽1(GLP-1)和糖依赖性胰岛素释放肽......
α及母细胞功能障碍在2型糖尿病的发生中发挥重要作用.二肽基肽酶4( DPP-4)抑制剂是一类基于肠促胰素的新型的口服降糖药物,通过增......
肠促胰岛素作为一类新型降糖药备受关注,根据作用机制分为胰高血糖素样肤1(GLP-1)受体激动剂和二肽基肽酶4(DPP-4)抑制剂两类.这两......
胰升糖素样肽1(GLP-1)受体激动剂和二肽基肽酶4(DPP-4)抑制剂是基于肠促胰素治疗2型糖尿病的2类药物,GLP-1受体激动剂可直接激活GL......
Dipeptidyl peptidase-4 (DPP-4) is a membrane-associated peptidase, also known as CD26. DPP-4 has widespread organ distri......
胰高血糖素样肽-1是近年来2型糖尿病治疗方面的研究热点之一。它是由小肠上皮L细胞分泌的一种肽类物质,对维持餐后血糖和控制食欲......
Development of therapeutic options on type 2 diabetes in years: Glucagon-like peptide-1 receptor ago
Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia.Type 2 diabetes (T2DM) accounting f......
<正>目的:初步探讨不同饮食负荷对正常糖耐量人群的葡萄糖依赖性促胰岛素分泌多肽(glucose-dependent insulinotropicploypeptide,......
会议
肠促胰岛素(Incretin)具有进食后刺激胰岛素分泌、促进胰岛素生物合成和抑制胰高血糖素分泌等多种生理功能,在维持血糖稳态上发挥了重......
Effects of extracellular matrix proteins on expansion, proliferation and insulin-producing-cell diff
Regeneration of transplantable pancreatic islet cells has been considered to be a promising alternative therapy for type......
Can Sitaglipten Attenuate Hypertension, Myocardial Changes and Vascular Reactivity Induced by Long T
Background: Glucagon-like peptide-1 (GLP-1) is an incretin hormone with insulinotropic properties that regulates glucose......
DPP-4 Inhibition Ameliorates Pancreatic β-Cell Failure and Improves Glucose Tolerance in the Mouse M
Wolfram syndrome, an autosomal recessive disorder associated with diabetes and optic atrophy, is caused by mutations in ......
DPP-4 Inhibition Ameliorates Pancreatic β-Cell Failure and Improves Glucose Tolerance in the Mouse M
Wolfram syndrome, an autosomal recessive disorder associated with diabetes and optic atrophy, is caused by mutations in ......
Type 2 diabetes is one of the most prevalent and serious metabolic diseases.Under diabetic conditions,chronic hyperglyce......
The gastrointestinal tract is the key interface between the ingesta and the human body.There is wide recognition that th......
New perspectives on exploitation of incretin peptides for the treatment of diabetes and related diso
The applicability of stable gut hormones for the treatment of obesity-related diabetes is now undisputable. This is base......
Incretin-based therapies have revolutionized the medicalmanagement of type 2 diabetes mellitus (T2DM)in the 21st century. ......