Isonucleoside相关论文
Biological Effects of Conformational Alteration Induced by D-L-Isonucleoside or 2-Deoxvinosine Incor
The silencing activities of modified siRNAs(siMekl s, etc) with D-/L-isoNA at several positions of antisense strand drop......
人工合成的寡核苷酸,包括反义寡核苷酸、干扰RNA等,显示了优异的临床潜在应用价值但要实现合成的寡核苷酸的广泛临床应用,必须要克......
目的研究异核苷的掺入对DNA:DNA双链的结构特征以及杂交热稳定性的影响。方法对含有16个碱基序列的DNA:DNA杂交双链d(T)16:d(A)16(DO:D)以及......
目的合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力.方法采用DNA固相合成仪合成寡核苷酸,通过热变性实验考察双链的稳定......
NMR Study on Fluoroisonucleosides( I)——Determination of the Configuration and Conformation of 1’ -a-
The present paper reports the determination of the configuration and Conformation of 1’ -a-methoxy-2’ -deoxy-2’-β-fl......