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Anti-Parkinsonian effects of Polygonum multiflorum Thunb.on transgenic and pharmacological Caenorhab
Objective: Polygonum multiflorum Thunb.is more commonly used in Chinese herbs/constituents (e.g.Kang Zhen Zhi Jing No.1 ......
Treatment with epigenetic factors of 5-aza-deoxycytidine and TSA sensitize neurotoxic effects of neu
Parkinsons disease (PD) is a progressive neurodegenerative disease related to age,which primarily results from the death......
Parkinsons disease(PD)is a progressive,neurodegenerative disorder of unknown etiology although a complex interaction......
Fungi are important infectious disease-causing agents, but are often overlooked as environmental factors in disease. We ......
Organophosphates (OPs) and Pyrethroids (PRY) have been widely used in agriculture and in the home as broad spectrum inse......
肠道菌群(gut microbiota,GM)是指共生于人体消化道中的大量微生物,GM紊乱和多种疾病有关。最近的研究发现,阿尔茨海默病(Alzheimer′s d......
目的观察新型基因重组海葵毒素rhk2a对大鼠心室肌细胞离子通道的影响.方法采用全细胞膜片钳技术分别记录rhk2a对大鼠心室肌细胞钠......
文中主要研究了毕赤酵母基因工程菌的构建及其发酵表达产物蛇神经毒素的分离纯化条件.蛇神经毒素编码基因由本实验室设计、合成,并......
目的研究何首乌提取物对鱼藤酮所致帕金森病线虫模型的神经保护作用。方法设对照组、鱼藤酮组和用药组(0.5 g/L,1.0 g/L),观察其对线......
目的:观察N-甲基-D-天冬氨酸(NMDA)对耳蜗电位的影响,探讨NMDA对耳蜗的神经毒性作用.方法:用圆窗电极测试耳蜗的基础复合动作电位(......
海葵神经毒素是一类能特异作用于神经和肌肉可兴奋细胞膜上的关键靶位即神经受体或离子通道,从而影响生物生理功能的多肽类毒素。......
随着近年来水体内藻类频繁暴发,藻类产生的毒素逐渐成为关注的热点。其中藻源神经毒素的毒性大、作用快,对人类、牲畜都有严重危害......
Fungi are important infectious disease-causing agents,but are often overlooked as environmental factors in disease.We re......
目的观察新型基因重组海葵毒素rhk2a对大鼠心室肌细胞离子通道的影响.方法采用全细胞膜片钳技术分别记录rhk2a对大鼠心室肌细胞钠......