SYNAPTIC相关论文
Substance P (SP),the first identified neuropeptide,has long been indicated to be involved in the vagal control of heart ......
Activation of α7 nAChR by PNU improves synaptic and cognitive function through restoring the express
OBJECTIVE Alzheimer disease(AD)is the most common type of dementia and is featured by the accumulation of β-amyloid pep......
围手术期神经认知障碍（perioperative neurocognitive disorder, PND）发生率高，危害大，但机制不清，阐明其病理机制，研发有效的防治措施具......
Ibrutinib alleviated LPS-induced neuroinflam⁃mation and synaptic defects in mouse model of depressio
OBJECTIVE Previous studies have demonstrated a close association between an altered immune system and major depressive d......
Regulatory role of sorting nexin 5 in protein stability and vesicular targeting of vesicular acetylc
Accurate targeting of vesicular acetylcholine transporter(VAChT)to synaptic vesicles(SVs)is indispensable for efficient ......
CCL2/CCR2 Contributes to the Altered Excitatory-inhibitory Synaptic Balance in the Nucleus Accumbens
The medium spiny neurons(MSNs)in the nucleus accumbens(NAc)integrate excitatory and inhibitory synaptic inputs and gate ......
The synapse of human brain neurons is not only the transmission channel of information,but also the basic unit of human ......
Preserving GABAergic interneurons in acute brain slices of mice using the N-methyl-D-glucamine-based
Defects in the function and development of GABAergic interneurons have been linked to psychiatric disorders, so preserva......
In the nervous system, neurons contact each other to form neuronal circuits and drive behavior, relying heavily on synap......
Low-frequency transcranial magnetic stimulation is beneficial for enhancing synaptic plasticity in t
In the aging brain, cognitive function gradually declines and causes a progressive reduction in the structural and funct......
Influence of environmental enrichment on hippocampal synapses in adolescent offspring of mothers exp
Environmental enrichment attenuates hippocampal synaptic injury induced by prenatal stress in offspring. However, the in......
Environmental enrichment promotes neural remodeling in newborn rats with hypoxic-ischemic brain dama
We evaluated the effect of hypoxic-ischemic brain damage and treatment with early environmental enrichment intervention ......
Short-Term Synaptic Plasticity Mimicked on Ionic/Electronic Hybrid Oxide Synaptic Transistor Gated b
An indium e zinc-oxide(IZO) based ionic/electronic hybrid synaptic transistor gated by field-configurable nanogranular S......
Effects of the ephedra alkaloid methylephedrine on the basal evoked potential transportation and the
Objective The effect of the ephedra/ephedrine alkaloid methylephedrine(dl-methylephedrine hydrochloride for testing in t......
Terminalia arjuna bark extract attenuates picrotoxin-induced behavioral changes by activation of ser
Stress and emotion are associated with several illnesses from headaches to heart diseases and immune deficiencies to cen......
Fructose-1,6-diphosphate is a metabolic intermediate that promotes cell metabolism. We hypothesize that fructose-1,6-dip......
Association Analysis of Genetic Variant of rs13331 in PSD95 Gene with Autism Spectrum Disorders:A Ca
Autism spectrum disorder(ASD) is a neurodevelopmental disorder characterized by high heritability. Recently, autism, the......
Changes of learning and memory ability associated with neuronal nitric oxide synthase in brain tissu
BACKGROUD: Ethanol can influence neural development and the ability of learning and memory, but its mechanism of the neu......
Autism spectrum disorder(ASD) encompasses a complex set of developmental neurological disorders,characterized by de?cits......
Therapeutic potential of brain-derived neurotrophic factor(BDNF) and a small molecular mimics of BDN
Traumatic brain injury(TBI) is a major health problem worldwide.Following primary mechanical insults,a cascade of second......
N-甲基-D-天门冬氨酸受体(N-methyl-D-aspartate receptors,NMDARs)是中枢神经系统中最重要的谷氨酸受体之一,属于配体和电压双门......
Inhibitory interneurons,which count 10%—20%of neurons in cortex,regulate the firing of excitatory neurons and are criti......
The toxicity of amyloid-beta(Aβ)is strongly associated with Alzheimer’s disease(AD),which has a high incidence in the ......
N-Methyl-D-aspartate receptors(NMDARs)play vital roles in the central nervous system,as they are primary mediators of Ca......
Caspases, a family of cysteine proteases, mediate programmed cell death during early neural development and neurodegener......
Over the past decades,continuous effort has been made to resolve unsettled matters in the emerging scene of neuronal dev......
N-methyl-D-aspartate receptors(NMDARs) containing different GluN2 subunits play distinct roles in synaptic plasticity.Su......
Spatial and temporal plasticity of synaptic organization in anterior cingulate cortex following peri
To explore whether experiencing inflammatory pain has an impact upon intracortical synaptic organization,the planar mult......
Evidence suggests that the deterioration of communication between the sympathetic nervous system and cardiovascular syst......
Type 2 diabetes(T2D)is an important risk factor for developing dementias,including Alzheimer’s disease(AD).Hyperinsulin......
In this study,we have formulated the phase description of the neuronal oscillator with non-instantaneous synaptic inputs......
Short-Term Memory(STM) is a primary capability of the human brain. Humans use STM to remember a small amount of informat......
Properties that are similar to the memory and learning functions in biological systems have been observed and reported i......
Redox-altered plasticity refers to redox-dependent reversible changes in synaptic plasticity via altering functions of k......
Long-term potentiation(LTP)at synapses between primary afferents and spinal dorsal horn neurons induced by noxious elect......
Dear Editor, The retina is one of the highest oxygen-consuming tissues in the body because the visual process in the ver......
A proteomics analysis for certain signature proteins of rabbit lacrimal passages after ~(125)I seeds
To search for certain signature proteins and the expression profiles in lacrimal passage stenosis,rabbit models of lacri......
The development of cell replacement techniques is promising as a potential treatment for photoreceptor loss. However, th......
Lambda-cyhalothrin disrupts the up-regulation effect of 17β-estradiol on post-synaptic density 95 pr
Lambda-cyhalothrin(LCT),one of the type II pyrethroids,has been widely used throughout the world.The estrogenic effect o......
Changes in behaviors of rats with sciatic nerve injury and expression of growth associated protein-4
BACKGROUND: Neuropathic pain is closely related to neuroplasticity, and growth associated protein-43 (GAP 43) is a molec......
Sexual differences of the effects of prenatal stress on the expression of extracellular signal-regul
BACKGROUND: Prenatal stress has been shown to inhibit cell proliferation in the dentate gyrus and hippocampus, reduce hi......
Presynaptic inhibition of nociceptive neurotransmission by somatosensory neuron-secreted suppressors
Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons......
This paper concerns certain difficult problems in image processing and perception: neuro-computation of visual motion in......
Action potentials of type C spinal ganglion neurons and their responses to high magnesium and low ca
Dorsal root ganglion (DRG) neurons may be divided into rapidly conducting type A and slowly conducting type C neurons i......
Being the functional basis of neural networks, neuronal signal integration has been currently becoming a hot point of n......
Aim: Hippocampal long-term potentiation (LTP), an activity-dependent plasticity in synaptic transmission, is believed a......
Inhibitory effect of morphine on excitatory synaptic transmission via presynaptic mechanism in rat S
Objective: To observe the effects of morphine on the excitatory postsynaptic currents (EPSCs) and miniature EPSCs (mEPSC......
长时程增强(LTP)是学习和记忆过程的分子水平现象。参与LTP机制的因素很多,最近研究发现神经趋向因子,特别是其中的脑衍生的神经趋......
