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Evolution of the ErbB gene family and analysis of regulators of Egfr expression during development o
Egfr, a member of the ErbB gene family, plays a critical role in tissue development and homeostasis, wound healing, and ......
Mapping of de novo mutations in primary biliary cholangitis to a disease-specific co-expression netw
Primary biliary cholangitis(PBC)is an autoimmune disease involving dysregulation of a broad array of homeostatic and met......
Evolution of pectin synthesis relevant galacturonosyltransferase gene family and its expression duri
Background:Pectin is a key substance involved in cell wall development,and the galacturonosyltransferases(GAUTs)gene fam......
目的 探讨谷胱甘肽硫转移酶P1 (GSTP1)基因启动子区DNA甲基化、mRNA和蛋白表达与砷中毒的关系.方法 123例砷中毒患者来自贵州省兴......
AIM: Signal transducers and activators of transcription (STATs) are a family of transcription factors activated in respo......
目的 探讨胰腺癌细胞株中Hedgehog信号通路活化与K-ras基因突变的相关性.方法 采用实时定量PCR法检测人胰腺癌细胞株SW1990、PaTu8......
,Expression profiles of genes involved in jasmonic acid biosynthesis and signaling during growth and
...
Background:The transcription factor paired box 8 (PAX8) was associated with type 2 congenital non-goitrous hypothyroidis......
目的：探讨肝癌组织中胰岛素样生长因子Ⅱ（ IGF-Ⅱ）基因P4启动子甲基化状态及其与P4 mRNA表达的关系。方法收集行手术治疗的43例肝癌组......
传统观点认为:淋巴细胞通过淋巴组织和非淋巴组织的循环实现机体免疫调节和防御功能。近年来发现了一群长期定居于外周组织的淋巴......
试验旨在了解猪链球菌4型(Streptococcus suis serotype 4,SS4)转录调控因子GalR蛋白生物学信息并对其进行原核表达。使用相关生物......
长时间暴露于氧气中可导致急性肺损伤的发生，目前对于高氧诱导的急性肺损伤的发病机制尚未完全明确，且缺乏有效的治疗措施。本文就近......
目的探讨nm23-H1基因表达与大肠癌生物学行为及预后的关系.方法应用抗nm23-H1单克隆抗体,采用免疫组化ABC方法对121例大肠癌组织进......
Role of the Arabidopsis thafiana NAC transcription factors ANAC019 and ANAC055 in regulating jasmoni
Jasmonic 酸(JA ) 是对草食动物攻击，病原体感染并且机械伤害调整植物防卫回答的重要植物激素。在这份报告，我们提供了生物化学、基......
为探索鱼类转铁蛋白基因tf和转铁蛋白受体基因tfr1a的转录调控机制,本实验以团头鲂为研究对象,在其全基因组数据库中获取tf和tfr1a......
【目的】掌握禽呼肠孤病毒（ARV）感染SPF鸡后免疫器官中白细胞介素18（IL-18）的相对动态转录时相,为揭示ARV的致病机制奠定基础。【方法......
目的：研究F10基因对转录因子NF-κB、AP1活性的影响。方法：质脂体共转染F10基因和报道质粒NF-κB-Luc、AP1-Luc，通过测定荧光素酶的活......
目的筛选与肾移植急性排斥反应相关的转录因子。方法应用转录因子芯片技术,在功能水平分析3份肾移植急性排斥反应患者病理组织与3......
目的：构建缺失激素结合区（LBD）的人糖皮质激素受体突变体表达载体，并研究其表达和功能。方法：运用RT-nested PCR扩增人糖皮质激素受体（CR......
以中国西门塔尔牛基因组DNA为模板,参照绵羊的FSHR基因序列设计和合成引物,PCR扩增获得长度为931 bp,包括5′端侧翼797 bp和结构基......
目的：构建含血管内皮生长因子（VEGF）基因启动子的荧光素酶报告基因载体，并检测其在雌激素受体作用下的转录活性。方法：以乳腺癌细胞系MC......
Detection of hepatocellular carcinoma cells in the peripheral blood with reverse--transcription poly
...
综述了线粒体中抗氧化关键酶含锰趟氧化物歧化酶基因的结构特点及各种因素对其转录调控的机制，以期为提高机体抗氧化能力、减少细胞......
Summary: In order to investigate the relationship between the expression of heme oxygenase-2 (HO-2) mRNA and the pathoge......
目的：探讨转录激活因子3（STAT3）及X线修复交叉互补基因4（XRCC4）基因多态性与中国人群肝细胞癌（HCC）易感性的关系。方法采用病例对照研究，以......
目的 从T淋巴细胞分化的多环节观察儿童自身免疫性甲状腺疾病Graves病（GD）和桥本甲状腺炎（HT）Th1／Th2类细胞的极化偏移方向，探讨其免疫学......
The diagnosis of gastric metastasis from lung cancer is relatively rare in living patients.We describe a case of Type 4 ......
哺乳动物雷帕霉素靶蛋白（mTOR）是一种重要的信号分子,参与体内蛋白质合成,细胞增殖、细胞周期、能量代谢和自噬等过程.mTOR的失活可......
Renoprotective and Blood Pressure Lowering Impact of Equisetum arvense and Viscum album Therapy in E
Background: Chronic kidney disease (CKD) is an irreversible decline in the glomerular filtration due to nephrosclerosis ......
The paramyxoviruses are a family of>30 viruses that variously infect humans,other mammals and fish to cause diverse outc......
