Tetrahydroisoquinoline相关论文
A versatile and efficient telescoped reaction sequence for the synthesis of tetrahydroisoquinolines (THIQs) is reported ......
N-烷基胺的氧化官能团化是形成碳-碳键和碳-杂原子键的最直接和通用的策略之一.近年来,N-烷基胺类作为多功能砌块在交叉脱氢偶联(C......
目的:合成新型四氢异喹啉类化合物,并研究其抗肿瘤活性。方法:以3,4-二甲氧基苯乙胺、一系列苯甲酸衍生物和肉桂酸衍生物为原料,用Bi......
目的建立同时测定猫豆中左旋多巴(2)及其3种衍生物含量的高效液相色谱法。方法从猫豆中分离获得3-羧基-6,7-二羟基-1,2,3,4-四氢异......
An Efficient Synthetic Strategy for Construction of Functionalized Pentacyclic Skeleton of ecteinasc
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的:研究脂肪酸四氢异喹啉的多药耐药活性.方法:利用Bischler-Napieralski环化反应合成一系列具有C-1长链烷基的四氢异喹啉衍生物......
An Efficient Synthetic Strategy for Construction of Functionalized Pentacyclic Skeleton of ecteinasc
Two functionalized pentacyclic compounds 12a, 12b were constructed via a highly efficient synthetic route, employing a t......
An analog of phthalascidin (Pt-650) was synthesized with an improved synthetic route.With precursor 2 as the starting ma......
目的:研究脂肪酸四氢异喹啉的多药耐药活性。方法:利用Bischler-Napieralski环化反应合成一系列具有C-1长链烷基的四氢异喹啉衍生......
以具心血管活性的异喹啉生物碱为先导物,设计合成了10个未见文献报道的1-(4-酰氧基苄基)四氢异喹啉类化合物,结构经元素分析、红外光谱、核磁......
目的:观察新合成四氢异喹啉衍生物H108抑制P-糖蛋白(P-gp)功能及对PC12细胞损伤的保护作用.方法:测定H108对K562/ADR细胞株及大鼠......
1位酯基取代、氮上烷基取代的四氢异喹啉在与碘甲烷成盐后不发生通常的Stevens重排反应,而是酯基α位烯醇化后发生氧烷基化反应,生......
以(S)-1-苯基-1,2,3,4-四氢异喹啉为起始原料,经亲核加成消除反应成酯,再与氨苄进行胺解交换反应得到目标化合物Solifenacin-1801......
Enantioselective addition of diethylzinc to aryl aldehydes catalyzed by 1,2,3,4-tetrahydroisoquinoli
A highly effective,new chiral 1,2,3,4-tetrahydroisoquinoline catalyst 1 for the diethylzinc addition to aryl aldehydes h......
以(±)-1-[(苯甲酰氨基)甲基]-1,2,3,4-四氢异喹啉(BTIQ)为原料,用光学纯L-(-)-樟脑磺酸为拆分剂,在丙酮中生成(-)BTIQ樟脑磺酸盐。最后......
目的获得1-[(苯甲酰氨基)甲基]-1,2,3,4-四氢异喹啉(BTIQ)的2种旋光异构体。方法以(±)BTIQ为原料,光学纯樟脑磺酸为拆分剂,在......
Synthesis and Evaluation of Anticonvulsant Activity of 6,8-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoq
This study we describe the synthesis of a novel structure of anticonvulsant agent as 6,8-dimethoxy-3-methyl-1,2,3,4- tet......