adalimumab相关论文
多种生物制剂已被批准用于治疗炎症性肠病（IBD）。但由于缺乏比较生物制剂间疗效和安全性的头对头的随机对照研究，以及缺乏准确预测生......
目的:评估阿达木单抗(ADA)治疗克罗恩病的有效性和安全性，并分析ADA疗效的预测因素。方法:连续纳入2020年1至12月于同济大学附属第......
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报道2017年8月至2019年12月第四军医大学西京皮肤医院收治的4例化脓性汗腺炎，年龄20 ~ 45岁，均为男性，皮损表现为腋窝、臀部、腹股沟......
目的探讨阿达木单抗对活动性类风湿关节炎患者血清炎症指标的影响。方法抽取2020年1月至2020年11月郑州人民医院收治的活动性类风......
Adalimumab induction therapy for ulcerative colitis with intolerance or lost response to infliximab:
AIM: To evaluate the efficacy of adalimumab induction therapy in patients with ulcerative colitis who previously respond......
Infliximab (IFX) is currently the only biologic therapy used in the treatment of moderate-to-severe ulcerative colitis (......
患者女,27岁。全身红斑鳞屑10余年,加重伴脓疱、发热10天。诊断:急性泛发性脓疱型银屑病。该例患者皮疹多样,包括红斑、大斑块、脓......
构建阿达木单抗抗原结合片段(Fragment antigen binding,Fab)表达载体,使其在大肠杆菌内高效共分泌表达,周质空间中获得具有活性的......
Crohns disease (CD) is a chronic relapsing and remitting autoinflammatory disorder of the gastrointestinal tract that ha......
阿达木单抗(adalimumab,ADA)是一种抗肿瘤坏死因子-α(TNF-α)的重组IgG1,是完全人源化的单克隆抗体,对可溶性及膜性TNF-α有高度......
目的:系统评价阿达木单抗注射液治疗关节病型银屑病的疗效及安全性。方法:通过计算机检索中文期刊全文数据库(CNKI)、万方数据库、......
目的评价古塞奇尤单抗治疗中重度斑块状银屑病的疗效与安全性。方法检索PubMed、www.clinctrials.gov、Cochrane Library、中国知......
反肿瘤坏死因素(TNF ) 高山哈药处于众多的长期的煽动性的条件在宽恕和它的维护的正式就职表明功效。与收到 anti-TNFalpha 代理人......
Successful use of adalimumab for treating fistulizing Crohn＇s disease with pyoderma gangrenosum： Two
背景：训练的整个身体颤动(WBV ) 出现到豆子为在更老的个人训练的常规抵抗的有效选择。到目前为止，没有数据在心和肺的健康上关于振......
瞄准：在 adalimumab 失败以后在 Crohns 疾病病人作为第二线的治疗评估 infliximab 的有效性。方法：在一个基于社区的肠胃病学惯例的......
反肿瘤坏死因素的使用 -- 自从国家合作 Crohns 疾病学习的出版，为煽动性的肠疾病的治疗三十年以前由这些病人照料代表最重要的进展......
Tumor necrosis factor-α(TNF-α)inhibitors are known to increase reactivation of concurrent chronic hepatitis B,but thei......
Intestinal Behet’s disease appearing during treatment with adalimumab in a patient with ankylosing s
Behet’s disease(BD)is a chronic inflammatory disease affecting multiple organ systems,such as the skin,joints,blood v......
Varicella zoster meningitis complicating combined anti-tumor necrosis factor and corticosteroid ther
Opportunistic viral infections are a well-recognized complication of anti-tumor necrosis factor (TNF) therapy for inflam......
Clinical effects of adalimumab treatment with concomitant azathioprine in Japanese Crohn’s disease p
AIM:To assess adalimumab’s efficacy with concomitant azathioprine (AZA) for induction and maintenance of clinical remis......
AIM To analyze 1-year liver injury burden in inflammatory bowel disease(IBD) patients. METHODS During a 6-mo inclusion p......
Trefoil factor-3 is not a useful marker of mucosal healing in Crohn’s disease treated with anti-TNF-
AIM To evaluate whether repeated serum measurements of trefoil factor-3(TFF-3)can reliably reflect mucosal healing(MH)in......
Trefoil factor-3 is not a useful marker of mucosal healing in Crohn’s disease treated with anti-TNF-
AIM To evaluate whether repeated serum measurements of trefoil factor-3(TFF-3)can reliably reflect mucosal healing(MH)in......
Biologic compounds are obtained from living organisms or cell cultures by means of biotechnology methods.A similar biolo......
背景：国外一系列随机对照试验（RCT）比较了阿达木单抗和安慰剂治疗成人中重度克罗恩病（CD）的疗效和安全性，但目前尚无统一结论。目的：对阿......
阿达木抗体是一种特异性靶向人肿瘤坏死因子TNF-α的全人源单克隆抗体类药物.近年来先后被美国和欧盟批准用于类风湿关节炎、克罗......
目的观察阿达木单抗对强直性脊柱炎(AS)患者骨代谢标志物的影响。方法随机选取2014年1月至2017年12月长海医院风湿免疫科收治的活......
意大利罗马大学的Marina Papoutsaki博士及其同事于8月的《美国皮肤病学学会杂志》（J Am Acad Dermatol，2007；57：269-275．）上报道，阿达木......
美国生物技术巨头艾伯维（AbbVie）旗舰产品Humira（修美乐，通用名：adalimumab，阿达木单抗）近日在美国和欧盟监管方面同时传来喜讯。美国方面......
艾伯维（AbbVie）5月20日宣布，FDA已授予Humira（修美乐，通用名：adalimumab，阿达木单抗）治疗非感染性中、后或泛葡萄膜炎或慢性非感染性前葡萄......
Ulcerative colitis(UC) is an immune-mediated, chronic inflammatory disease of the large intestine. Its course is charact......
Anti-tumour necrosis factor-α(TNF) therapy has revolutionised the management of chronic inflammatory conditions.With ev......
Gastroduodenal Crohn’s disease (CD) is rare and the response to standard medical therapy is often poor. Anti-tumor necr......
There are several reports of anti-tumor necrosis factor(TNF)-induced lung disease,especially in patients with rheumatolo......
There are several reports of anti-tumor necrosis factor(TNF)-induced lung disease,especially in patients with rheumatolo......
阿达木单抗是一种可与TNF-α特异性结合从而阻断自身免疫炎症反应的蛋白质药物。这种药物在冻干过程中结构不稳定且容易失活,严重......
We present a case of tuberculous peritonitis in a 46-year-old woman with rheumatoid arthritis treated with adalimumab, a......
We present a case of tuberculous peritonitis in a 46-year-old woman with rheumatoid arthritis treated with adalimumab, a......
First United Arab Emirates consensus on diagnosis and management of inflammatory bowel diseases:A 20
Ulcerative colitis and Crohn’s disease are the main entities of inflammatory bowel disease characterized by chronic rem......
Elevation of liver biochemistry has been reported with anti-tumor necrosis factor agents, but overt liver failure rarely......
克罗恩病（CD）与遗传、免疫、肠茵等多因素相互作用有关，近年来，随着对CD病理生理学状况了解的加深，许多有效的生物学治疗方法已经应用于......
This article describes cases of anti-tumor necrosis factor（TNF）-α-induced autoimmune hepatitis and evaluatesthe outcome o......
Growth and bone health in paediatric patients with Crohn＇sdisease receiving subcutaneous tumor necro
AIM To study whether adalimumab （ADA） wasassociated with improvement in growth, bone mineral density （BMD） and bone metaboli......
美国FDA于2019年11月15日批准一种新的生物仿制药(biosimilar)产品Abrilada(adalimumab - afzb),其仿制对象是Humira(adalimumab,......
据报道，从已经得到的Ⅲ期临床研究数据分析，Abbott公司三年前上市的、对处于活动期的成人中度或重度的类风湿性关节炎及关节强硬性脊......
1商品名Humira2结构特点本品为抗人肿瘤坏死因子(TNF)的人源化单克隆抗体,是人单克隆D2E7重链和轻链经二硫键结合的二聚物.......
Background: Traditionally, management of Juvenile Idiopathic Arthritis (JIA) involves use of non-steroidal anti-inflamma......
帕洛诺司琼 palonosetron；曲妥珠单抗 trastuzumab；阿达木单抗 adalimumab；阿立哌唑 aripirazole...
