efavirenz相关论文
Switching from efavirenz to elvitegravir/cobicistat/emtricitabine/ tenofovir alafenamide reduces cen
Background::Central nervous system (CNS) symptoms after efavirenz (EFV) treatment in people living with human immunodefi......
Efavirenz,trade name Stocrin,is one of the non-nucleoside HIV-1 reverse transcriptase inhibitor which is widely used in ......
OG-PP30:Enantioselective Trifluoromethylation of Carbonyls and Its Application to HIV-1 reverse tran
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Switching from efavirenz to elvitegravir/cobicistat/emtricitabine/ tenofovir alafenamide reduces cen
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ＤｕＰｏｎｔ公司的非核苷类逆转录酶抑制剂Ｅｆａｖｉｒｅｎｚ目前已获得美国ＦＤＡ的批准，用于治疗成人或儿童的ＨＩＶ感染和ＡＩＤＳ。每天服用１次，食物对其无影响，可与蛋白酶抑制剂和／或......
目的 研究中国健康人CYP2B6*6基因多态性对依法韦仑药动学的影响.方法 应用聚合酶链反应-限制性片段长度多态性分析(PCR-RFLP)将40......
目的 评价非核苷逆转录酶抑制剂依非韦仑 (efavirenz, EFV) 在妊娠早期抗逆转录病毒治疗 (antiretroviral therapy, ART) 中的安全......
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believe......
Objective: To investigate the influence of ABCB1 polymorphisms on the plasma level of efavirenz in Thai adult cases infe......
目的:探讨拉米夫定、替诺福韦联合依非韦伦治疗不同免疫功能艾滋病的效果。方法:回顾性分析2017年1月-2019年12月在本院建档领取药......
对于婴儿和年龄较小的儿童来说,基于利托那韦辅助洛匹那韦的（ritonavirboosted lopinavir）治疗方法是推荐使用的一线抗逆转录病毒治......
目的:研究利福布汀(RBT)与依非韦伦(EFV)在大鼠体内药动学的相互影响。方法:将大鼠随机分为EFV单用组(54mg·kg-1)、RBT单用组(40.......
目的：研究拉米夫定、依非韦伦、替诺福韦与牛血清白蛋白（BSA）的相互作用及其机制。方法：通过荧光光谱法研究不同温度下不同浓度的拉米......
Monitoring of Early Field Hepatic Tolerance to NNRTI-Based Regimens with Multiple Biochemical Parame
Background: Multiple biochemical parameters related to cytolysis, cholestasis and/or liver failure, can be used to evalu......
Immunological responses of HIV/AIDS patients treated with Nevirapine versus Efavirenz based highly a
Background: There are two approved non-nucleoside reverse transcriptase inhibitor antiretroviral drugs;namely Nevirapine......
Immunological responses of HIV/AIDS patients treated with Nevirapine versus Efavirenz based highly a
Background: There are two approved non-nucleoside reverse transcriptase inhibitor antiretroviral drugs;namely Nevirapine......
目的调查深圳地区艾滋病抗病毒治疗患者服用依非韦伦(efavirenz,EFV)标准剂量(600mg)后血浆中药物浓度与不良反应的相互关系,探索......
Aim: To describe the pharmacokinetic parameters of efavirenz and estimate its clearance (CL/F) accounting simultaneously......
Over Exposure to Efavirenz Plasma Concentrations among Beninese HIV Patients Treated by A 600 mg Dai
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目的探讨依非韦伦对肝细胞的毒性作用及对蛋白质表达谱的影响。方法人肝癌细胞系Huh7中分别加入依非韦伦1.25,2.5,5和10 mg.L-1,培......
A study was made to determine whether HIV-infected patients with prolonged virological control suffer subclinical neuroc......
A study was made to determine whether HIV-infected patients with prolonged virological control suffer subclinical neuroc......
Enhanced dissolution of poorly soluble antiviral drugs from nanoparticles of cellulose acetate based
Polysaccharide-based polymers were used to produce nanoparticles of poorly soluble antiviral drugs using a rapid precipi......
１ 商品名 Ｓｕｓｔｉｖａ２ 化学名 （１）－６－氯－４－环丙基乙炔基－４－三氟甲基－１，４－二氢－２Ｈ－３，１－苯并嗪－２－酮。３ 开发与上市厂商 （美）Ｍｅｒｃｋ公司研制，Ｄｕｐｏｎｔ公司上市。１９９９年２月在美国首次上市；同年７月在加拿......
第43届美国感染病学会年会上发表的Ⅲb期DART（Daily Antiretroviral Therapy）Ⅱ研究结果显示，每日一次应用Merck公司的efavirenz[Sust......
印度Aurobindo Pharma公司称，其有六个以上抗逆转录病毒药已被列入世界卫生组织的认证前列表中。这些产品包括efavirenz片剂600mg，拉......
据2005年7月在巴西召开的第三次世界艾滋病学会HIV发病机理及治疗大会上发表的一项公开标签研究结果，作为一线治疗方案，efavirenz（Ⅰ）......
