next-generation相关论文
Usefulness of metagenomic next-generation sequencing in adenovirus 7-induced acute respiratory distr
BACKGROUND Direct metagenomic next-generation sequencing(mNGS)of clinical samples is an effective method for the molecul......
Unusual immunohistochemical“null”pattern of four mismatch repair proteins in gastric cancer:A case r
BACKGROUND Immunohistochemical(IHC)staining for mismatch repair(MMR)proteins is useful for gastric cancer treatment and ......
FGFR2-TSC22D1,a novel FGFR2 fusion gene identified in a patient with colorectal cancer:A case report
BACKGROUND The FGFR signaling pathway is activated in multiple tumor types through gene amplifications,single base subst......
Gastrointestinal-type chemotherapy prolongs survival in an atypical primary ovarian mucinous carcino
BACKGROUND Primary ovarian mucinous carcinoma is a rare histologic subtype of epithelial ovarian carcinoma and exhibits ......
Use of DNA metabarcoding of bird pellets in understanding raptor diet on the Qinghai-Tibetan Plateau
Background:Diet analysis is essential to understanding the functional role of large bird species in food webs.Mor-pholog......
Rapid diagnosis of disseminated Mycobacterium mucogenicum infection in formalin-fixed, paraffin-embe
BACKGROUND Mycobacterium mucogenicum(M.mucogenicum)belongs to the group of rapidly growing Nontuberculous mycobacteria.T......
A targeted sequencing approach to find novel pathogenic genes associated with sporadic aortic dissec
Aortic dissection(AD)is a heterogeneous genetic disease of the aorta with high mortality and poor prognosis.However,only......
<strong>Background</strong><span style="font-family:Verdana;"><strong>:</strong></span><b><span style="font-family:""> <......
Background:Traditionally,scientists studied microbiology through the manner of batch cultures,to conclude the dynamics o......
BACKGROUND Cystic pancreatic lesions consist of a wide variety of lesions that are becoming increasingly diagnosed with ......
BACKGROUND Primary myelofibrosis(PMF)is a myeloproliferative neoplasm(MPN)characterized by recurrent mutations in the JA......
Genetic diagnosis history and osteoarticular phenotype of a nontransfusion secondary hemochromatosis
BACKGROUND It is not easy to identify the cause of various iron overload diseases because the phenotypes overlap.Therefo......
BACKGROUND There are many factors that lead to dwarfism,and the mechanism has not yet been elucidated.Next-generation se......
Clinical characteristics and ABCC2 genotype in Dubin-Johnson syndrome:A case report and review of th
BACKGROUND Dubin-Johnson syndrome(DJS)is a benign autosomal recessive liver disease involving mutations of the ABCC2 gen......
本草基因组计划（HerbGP）是针对具有典型代谢途径和重大经济价值的药用植物进行的全基因组测序和后基因组研究的系列计划。本文全面介......
针对下一代通讯网络EPC（ Evolved Packet Corenetwork）系统中AAA服务器通信协议的特点：同时支持Radius协议和Diameter协议,为了解决AA......
介绍了目前主流的高通量基因表达研究方法,以及不同基因组背景植物的普遍研究手段。...
Like other solid tumors,colorectal cancer(CRC) is a genomic disorder in which various types of genomic alterations,such ......
An updated review of gastric cancer in the next-generation sequencing era:Insights from bench to bed
Gastric cancer(GC)is one of the most common malignancies and remains the second leading cause of cancer-related death wo......
Gastric cancer is a complex disease that is affected bymultiple genetic and environmental factors. For theprecise diagno......
Genomic characterization of esophageal squamous cellcarcinoma： insights from next-generation sequenc
Two major types of cancer occur in the esophagussquamous cell carcinoma, which is associated withchronic smoking and alc......
Characterization of hepatitis B virus X gene quasispecies complexity in mono-infection and hepatitis
BACKGROUND Hepatitis delta virus (HDV) seems to strongly suppress hepatitis B virus (HBV) replication, although little i......
Application of next-generation sequencing technology to precision medicine in cancer: joint consensu
Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously......
In the new round of IT revolution, the AI industry has become a new engine driving economic growth. In such a context, m......
Recent advances and perspectives in next generation sequencing application to the genetic research o
Type 2 diabetes(T2D)mellitus is a common complex disease that currently affects more than 400 million people worldwide a......
Next-generation sequencing revealed specific microbial symbionts in Porites lutea with pigment abnor
Bacterial diseases affecting corals pose an enormous threat to the health of coral reefs. The relationship between certa......
Next generation sequencing for profiling expression of miRNAs: technical progress and applications i
miRNAs are non-coding RNAs that play a regulatory role in expression of genes and are associated with diseases. Quantita......
Cimicifuga simplex Wormsk. (Ranunculaceae) is a perennial herb distributed in eastern and northeastern Asia for which at......
Genome sequencing and next-generation sequence data analysis: A comprehensive compilation of bioinfo
Genomics has become a ground-breaking field in all areas of the life sciences. The advanced genomics and the development......
Fungi play a vital role in the management of soil environment. Although various fungal communities are found in soil, it......
Enhancer is a positive regulator for spatiotemporal development in eukaryotes.As a cluster,super‐enhancer is closely re......
Authentication is the first step,of central importance, for access control and for security protection in radio access n......
demand viewing of multimedia content over IP with browser-centric media endpoints introduces a new requirement for more ......
AIM To evaluate the genetic defects of ciliary genes causing the loss of primary cilium in autosomal dominant polycystic......
Next-generation sequencing(NGS) technologies have made high-throughput sequencing available to medium- and small-size la......
Eff ects of viral infection and microbial diversity on patients with sepsis:A retrospective study ba
BACKGROUND: The study aims to investigate the performance of a metagenomic next-generationsequencing (NGS)-based diagnos......
The arrival of both high-throughput and bench-top next-generation sequencing technologies and sequence enrichment method......
BACKGROUND Dental focal infection-induced ventricular and spinal canal empyema is an extremely rare,severe,acute disease......
Rice planthoppers,including brown planthopper(BPH)and white-backed planthopper(WBPH),are the most destructive pests in A......
Development and characterization of novel polymorphic microsatellite markers for the Korean freshwat
Korean freshwater snails of the genus Semisulcospira are widely distributed across East Asia.It has been a very popular ......
Efficacy of platinum in advanced triple-negative breast cancer with germline BRCA mutation determine
Objective:To compare the efficacy of platinum-and non-platinum-based regimens as first-line treatment for advanced tripl......
Genomic insights into hybridization in a localized region of sympatry between pewee sister species(C
Background: The Great Plains of the United States includes a large number of hybrid and contact zones between bird speci......
BACKGROUND Since it is currently not possible to eradicate hepatitis B virus(HBV)infection with existing treatments,rese......
Ehlers-Danlos syndrome(EDS)is a heterogeneous group of connective tissue disorders comprised of several types.Classic ED......
Dairy cows rely on a complex ruminal microbiota to digest their host-indigestible feed. Our ability to characterize this......
Composition and Diversity of Soil Bacterial Communities along an Environmental Gradient in the Sudan
The soils of the semi-arid Sudano-Sahelian region of West Africa have been identified as being highly vulnerable to soil......
CNV analysis of Meishan pig by nextgeneration sequencing and effects of AHR gene CNV on pig reproduc
Background:Reproductive performance of livestock is an economically important aspect of global food production.The Chine......
Viruses are a cause of significant health problem world-wide,especially in the developing nations.Due to different anthr......
In this commentary, I explain my perspective on the relationship between arti cial intelligence (AI)/data science and bi......
