off-target相关论文
Off-target effects are one of the most serious problems in RNA interference(RNAi)....
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siRNA的“脱靶效应”(off-target effects)是RNA干扰应用研究领域的热点问题.采用蛋白组学技术对质粒介导的siRNA稳定沉默原癌基因......
Site-directed RNA editing (SDRE) is invaluable to basic research and clinical applications and has emerged as a new fron......
CRISPR-mediated genome editing is a revolutionary technology for genome manipulation that uses the CRISPR-Cas systems an......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Polypharmacology, which focuses on designing drugs to target multiple receptors, has emerged as a new paradigm in drug d......
The CRISPR/Cas9 mediates efficient gene editing but has off-target effects inconducive to animal breeding. In this study......
提出了一种新型的与制程窗口紧密相关，被称为偏离最佳条件的基于模型的光学邻近效应模型，该模型包含制程参数变化的信息。该模型引导......
Rice(Oryza sativa L.)is an important staple food crop worldwide due to its adaptability to different environmental condi......
CRISPR gene editing is a technology used to edit genomes of a variety of organisms like bacteria,animals or even human b......
