论文部分内容阅读
This paper studied the synaptic and dendritic integration with different spatial distributions of synapses on the dendrites of a biophysically-detailed layer 5 pyramidal neuron model.It has been observed that temporally synchronous and spatially clustered synaptic inputs make dendrite perform a highly nonlinear integration.The effect of clustering degree of synaptic distribution on neuronal responsiveness was investigated by changing the number of dendrites where active synapses are allocated.The neuron shows maximum responsiveness to synaptic inputs which have an intermediate clustering degree of spatial distribution, indicating complex interactions among dendrites with the existence of nonlinear synaptic and dendritic integrations.