Objective Penicillin epilepsy model,whose discharge resembles that of human absence epilepsy,is one of the most useful acute experimental epilepsy models.
Mutations in SCN1A gene have been identified in epilepsies with widely variable severity,ranging from the extremely severe form of severe myoclonic epilepsy of infancy to the mild form of generalized
Congenital hypomyelinating leukodystrophies(HLDs)is a spectrum of genetic disorders with deficiency of myelin substantial deposit in brain white matter,causing development delay,nystagmus and/or other
Background: The pathophysiologic mechanisms of epileptogenesis,which starts from the beginning of brain damage to the chronic stage of spontaneous recurrent seizure(SRS),are still poorly understood.
Purpose: This article is to reveal behavioral,cognitive,spontaneously epilepsy,and electroencephalographic(EEG)characteristics in rats with malformations of cortical development(MCD),providing an idea