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Objective To discuss the diagnostic value of three-dimensional reconstructed technique with contrast enhancement of Dual-source CT(DSCT) in complex congenital heart disease(CCHD).Materials and Methods The MSCT data of 121 patients with CCHD confirmed by surgery were retrospectively analyzed.All patients were performed with transthoracic echocardiograms(TTE) and 68were compared with cineangiocardiograms(CAG) before surgery.Results A total of 425 cardiac deformities were found by operation.The accuracy of DSCT, TTE and CAG in detecting deformities was 96.9%,71.3%,and 95.8%, respectively.There were 238 intracardiac deformities,4 missed by DSCT,3 missed by TTE,and I missed by CAGThere was no significance difference in diagnosis accuracy with three methods (P>0.05).There were 187 extracardiac anomalies.The definite diagnosis rate ofMSCT, TTE and CAG for extracardiac anomalies were 97.5%,56.2%,and 96.6%,respectively.MSCT and CAG were superior to TTE in the identification of extracardiac deformties(P<0.01), and the diagnosis accuracy of MSCT and CAG showed no difference(P>0.05).MSCT combined with TTE could increase the definite diagnosis rate to 98.3%.Conclusion MSCT may be used to clearly display the pathologic anatomy of CCHD, which is superior toTTE remarkably in the diagnosis of extracardiac anomalies.Therefore,as a non-invasive technique,MSCT has a very higher diagnostic value in CCHD.