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  5. pH-responsive PEGylated doxorubicin for efficient cancer chemotherapy

pH-responsive PEGylated doxorubicin for efficient cancer chemotherapy

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：xblxr
【摘 要】
：
Poly(ethylene glycol) (PEG) with good biocompatibility and resistance to protein adsorption is the commonly used hydrophilic segment in nanocarriers for intravenous administration [1].PEG-modified dox
【作 者】
：
Zhiyu Zhang Xueyuan Gu Diankui Sun Jianxun Ding Qin Li Xiuli Zhuang Xuesi Chen 
【机 构】
：
Department of Orthopedics,4th Affiliated Hospital of China Medical University,Shenyang 110032,China
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
cancer therapy controlled release doxorubicin poly(ethylene glycol) pH-responsiv 
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　　Poly(ethylene glycol) (PEG) with good biocompatibility and resistance to protein adsorption is the commonly used hydrophilic segment in nanocarriers for intravenous administration [1].PEG-modified doxorubicin (DOX) has been a promising polymeric prodrug that exhibited improved DOX solubility,decreased side effects and enhanced efficacy [2].
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