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  5. Injectable chitosan thermogels for sustained and localized delivery of Pingyangmycin in vascular mal

Injectable chitosan thermogels for sustained and localized delivery of Pingyangmycin in vascular mal

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：woshoubei
【摘 要】
：
Pingyangmycin hydrochloride (PYM) is an effective sclerosing agent to treat vascularmalformations(VM), but can easily diffuse from the injection site, which will reduce the therapeutic effect of PYM a
【作 者】
：
Fen Chen Hongwei Wang Ling Zhang Xingjun Qin Weisan Pan 
【机 构】
：
Department of Pharmaceutics,School of Pharmacy,Shenyang Pharmaceutical University,Shenyang,110016,Ch
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
【关键词】
：
Pingyangmycin Chitosan Thermogels vascular malformations Chemoembolization EA.hy 
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　　Pingyangmycin hydrochloride (PYM) is an effective sclerosing agent to treat vascularmalformations(VM), but can easily diffuse from the injection site, which will reduce the therapeutic effect of PYM and increase its side effect.The purpose of our study was to evaluate the potential of PYM-loaded chitosan (CS) thermogels delivery system for interventional embolization therapy both in vitro and in vivo.
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