Porous carbon materials are considered to be very promising in numerous applications as adsorbents,catalyst supports,and double-layer capacitors due to its high surface area,open pore structure,light weight and low cost [1].It has also been reported that mesoporous (2–50 nm) carbon with open pore structure and large pore size has remarkable advantages in bulky molecular adsorption [2].The aim of this study was to evaluate the adsorption specificity of ordered mesoporous carbon (OMC) as solid phase extraction (SPE) adsorbents with tetracyclines as model analytes.The commercial obtained mesoporous carbon was characterized by nitrogen sorption isotherm (Fig.1 a) and small-angle XRD (Fig.1 b).The XRD result indicates that the carbon material is highly ordered.The nitrogen sorption isotherms show that the employed mesoporous carbon is typical 2-D hexagonal ordered structure.Then,the parameters affecting the adsorption efficiency,such as the pH of the sample,the amount of OMC,types and amount of elution solvent and elution speed,were investigated in detail.The optimal extraction conditions were as follows: 5 mg OMC as adsorbent,4 mL mixture of methanol and acetonitrile (v/v,1:1) as eluent (pH 10.0) at a speed of 0.7 mL min-1,sample pH 10.0.Under the optimal separation conditions,the three antibiotics could be baseline separated within 7 min (Fig.2).The linear range of the analytes varied from 1000 to 9000 μg L-1.The proposed SPE combined with capillary electrophoresis method was applied for the analysis of surface water samples with recoveries ranged from 44.1 % to119.6 % for the three tetracyclines.Compared with commercial SPE adsorbent (such as HLB and SAX),OMC presents higher sorption capacity accompanied with fewer consumption of adsorbent.The present work demonstrates that OMC is a promising adsorbing material in preconcentrating organic pollutatant from environmental samples.