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Lipid droplets (LD) are generally considered as the storage compartments for triacylglycerols (TAG) in eukaryotic cells.Microalgal LDs play numerous roles in cellular physiology, especially responses to stress by energy storage.Different from the increase numbers of LD in Chlamydomonas reinhardtii, the size of 2 or 3 LDs per cell enlarged with TAG accumulation under stress condition in Isochrysis zhangjiangensis.