Alzheimer disease(AD)has now become the most common brain disorder among the older population.In addition,the currently existing therapeutics only offer temporary symptomatic relieves.
The most common age-related neurodegenerative disease is Alzheimer disease(AD),the imbalance between Aβ generation and clearance accumulated in extracellular plaques(ECS).
OBJECTIVE Normal male aging is associated with declines in levels of the sex steroid hormone testosterone.A large body of evidence supports a neurotrophic role for testosterone in central nervous syst
OBJECTIVE Scalp mechanical stimulation,like combing,is one of the useful methods to keep brain health,which was historically recorded in traditional Chinese medicine thousand years ago.
OBJECTIVE Extracellular amyloid-β(Aβ)plaques are one of the major pathological hallmarks of Alzheim-er disease(AD).Therefore,decreasing Aβ levels is one strategyfor preventing the etiology of AD.
OBJECTIVE Alzheimer disease(AD)is the most common type of senile dementia.The anti-aging gene Klotho is reported to decline in the brain of patients and animals with AD.
Liuwei Dihuang decoction(LW),a classic formula in traditional Chinese medicine(TCM),has been used for nearly one thousand years for various diseases with characteristic features of kidney yin deficien
Tau oligomers are the etiologic molecules of Alzheimer disease(AD),and correlate strongly with neuro-nal loss and exhibit neurotoxicity.Recent evidence indicates that small tau oligomers are the most