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耐药结核病已成为严重威胁公共卫生的问题之一,呈现病程长、死亡率高、传染性强的特点。因此,对耐药结核病特别是耐多药结核病(MDR-TB)的研究成为当前重大课题。为进一步研究耐多药肺结核患者的病情与机体免疫状态的关系,探讨T淋巴细胞在疾病发生发展中的变化,我们用单克隆抗体法对30例耐多药肺结核患者外周血T淋巴细胞亚群进行了测定,并选用30例复治非耐多药肺结核做对照组,现将结果报告如下:
Drug-resistant tuberculosis (TB) has become one of the serious threats to public health, presenting with long duration, high mortality and high contagiousness. Therefore, the study of drug-resistant TB, especially MDR-TB, has become a major issue at present. To further study the relationship between MDR-TB patients and immune status, and to explore the changes of T-lymphocytes in the development of the disease, we used monoclonal antibody to detect the expression of T lymphocyte subsets in 30 MDR-TB patients Carried out the determination and selection of 30 cases of retreatment non-multi-drug resistant pulmonary tuberculosis as a control group, the results are reported as follows: